Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17398303 | 0.83 | DUT (0.37) | DUT | |
| SCHEMBL6709205 | 0.76 | HPGD (0.33) | BACE1 | |
| SCHEMBL29225646 | 0.75 | BACE1 (0.32) | BACE1 | |
| SCHEMBL1999481 | 0.74 | — | — | |
| SCHEMBL7723079 | 0.72 | DUT (0.36) | DUT | |
| SCHEMBL7421537 | 0.72 | — | — | |
| SCHEMBL1315036 | 0.72 | IDO1 (0.46) | BACE1 | |
| SCHEMBL232619 | 0.71 | — | — | |
| SCHEMBL28627546 | 0.71 | — | — | |
| SCHEMBL7716164 | 0.71 | DUT (0.38) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144360-B1 | A METHOD FOR THE SYNTHESIS OF COMPOUNDS OF FORMULA 1 AND DERIVATIVES THEREOF | PHARMACORE INC (US) | 2005-04-27 | — | — | EP | claimed |
| US-6391916-B1 | ANTITUMOR AGENTS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2002-05-21 | — | — | US | claimed |
| EP-3049386-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES | Universität zu Köln (DE) | 2016-08-03 | — | — | EP | disclosed |
| WO-2015044177-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES | UNIVERSITÄT ZU KÖLN (DE) | 2015-04-02 | — | — | WO | disclosed |
| US-20040087552-A1 | Pyrrolidine modulators of ccr5 chemokine receptor activity | MERCK SHARP & DOHME CORP. | 2004-05-06 | — | — | US | disclosed |
| US-20020094989-A1 | Pyrrolidine modulators of CCR5 chemokine receptor activity | HALE JEFFREY J (US) | 2002-07-18 | — | — | US | disclosed |
| US-6391916-B1 | ANTITUMOR AGENTS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2002-05-21 | — | — | US | disclosed |
| US-6197905-B1 | VINYL ETHER CHAIN TRANSFER AGENT TERMINATES THE GROWTH OF THE POLYMER CHAIN BY ADDITION TO THE PROPAGATING POLYMER RADICAL FOLLOWED BY EXPULSION OF A RADICAL WHICH THEN INITIATES ANOTHER POLYMER CHAIN | COMMONWEALTH SCIENTIFIC & INDUSTRIAL RESARCH ORGANIZATION (AU) | 2001-03-06 | — | — | US | disclosed |
| US-5932675-A | Free-radical chain transfer polymerization process | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1999-08-03 | — | — | US | disclosed |
| US-5874511-A | CHAIN TRANSFER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-02-23 | — | — | US | disclosed |
| EP-0333758-B1 | CONTROL OF MOLECULAR WEIGHT AND END GROUP FUNCTIONALITY OF POLYMERS | COMMW SCIENT IND RES ORG (AU) | 1995-11-02 | — | — | EP | disclosed |
| US-5385996-A | Control of molecular weight and end-group functionality of polymers | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1995-01-31 | — | — | US | disclosed |
| EP-0333758-A4 | CONTROL OF MOLECULAR WEIGHT AND END GROUP FUNCTIONALITY OF POLYMERS. | COMMW SCIENT IND RES ORG (AU) | 1990-05-14 | — | — | EP | disclosed |
| EP-0333758-A1 | CONTROL OF MOLECULAR WEIGHT AND END GROUP FUNCTIONALITY OF POLYMERS. | COMMW SCIENT IND RES ORG (AU) | 1989-09-27 | — | — | EP | disclosed |
| WO-1988004304-A1 | CONTROL OF MOLECULAR WEIGHT AND END GROUP FUNCTIONALITY OF POLYMERS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH OR (AU) | 1988-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020094989-A1 | Pyrrolidine modulators of CCR5 chemokine receptor activity | CCR5, CCR1, CXCR1 | BACE1 3982/4885DUT 1781/4885 |
| US-20040087552-A1 | Pyrrolidine modulators of ccr5 chemokine receptor activity | CCR5, CCR1, CXCR1 | BACE1 3869/4885DUT 1687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.