SCHEMBL6253264

SCHEMBL6253264

N=C(N)NC(O)(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.41
SRC P12931 1/20 0.41
MAPT P10636 4/20 0.39
BLM P54132 2/20 0.39
RECQL P46063 2/20 0.39
POLB P06746 2/20 0.39
F7 P08709 2/20 0.39
CYP3A4 P08684 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
TSHR P16473 2/20 0.39
F2 P00734 1/20 0.39
F10 P00742 1/20 0.39
F12 P00748 1/20 0.39
F3 P13726 1/20 0.39
PKM P14618 1/20 0.39
PARP1 P09874 1/20 0.39
CYP2C19 P33261 1/20 0.39
PMP22 Q01453 1/20 0.39
HSD17B10 Q99714 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1252890 0.82 CES1 (0.46) CES1SRCMAPTPOLBCYP3A4
SCHEMBL754131 0.79 CES1 (0.47) CES1SRCMAPTPOLBTSHR
SCHEMBL5483963 0.79 CES1 (0.46) CES1SRCMAPTBLMRECQL
SCHEMBL6447132 0.75 ALDH1A1 (0.45) CES1SRCPOLBCYP3A4TSHR
SCHEMBL5843722 0.75 ALDH1A1 (0.44) CES1SRCMAPTCYP2C19L3MBTL1
SCHEMBL1395461 0.75 CES1 (0.50) CES1SRCMAPTPOLBCYP3A4
SCHEMBL6438562 0.74 CES1 (0.42) CES1SRCMAPTPOLBTDP1
SCHEMBL7395954 0.74 CES1 (0.44) CES1SRCMAPTBLMRECQL
SCHEMBL27954225 0.72 ALDH1A1 (0.46) MAPTBLMRECQLPOLBCYP3A4
SCHEMBL5844361 0.72 EGFR (0.56) MAPTRECQLF3KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE38723-E1 Haloalkyl derivatives of reporter molecules used to analyze metabolic activity in cells MOLECULAR PROBES, INC. (US) 2005-04-12 US claimed
EP-0603266-B1 USE OF HALOALKYL DERIVATIVES OF REPORTER MOLECULES TO ANALYZE METABOLIC ACTIVITY IN CELLS MOLECULAR PROBES INC (US) 1999-05-12 EP claimed
US-5576424-A ANALYZING METABOLIC ACTIVITY OF ENZYMES MOLECULAR PROBES, INC. (US) 1996-11-19 US claimed
US-5362628-A Analyzing MOLECULAR PROBES, INC. (US) 1994-11-08 US claimed
US-10265434-B2 Absorbent articles comprising glyceride copolymers THE PROCTER & GAMBLE COMPANY (US) 2019-04-23 US disclosed
US-20180161474-A1 ABSORBENT ARTICLES COMPRISING GLYCERIDE COPOLYMERS THE PROCTER & GAMBLE COMPANY 2018-06-14 US disclosed
WO-2018013151-A1 ABSORBENT ARTICLES COMPRISING METATHESIZED UNSATURATED POLYOL ESTERS THE PROCTER & GAMBLE COMPANY (US) 2018-01-18 WO disclosed
US-20180008484-A1 ABSORBENT ARTICLES COMPRISING METATHESIZED UNSATURATED POLYOL ESTERS THE PROCTER & GAMBLE COMPANY 2018-01-11 US disclosed
CN-103502218-A Compounds and methods for conjugation of biomolecules LIFE TECHNOLOGIES CORP 2014-01-08 CN disclosed
CN-102051281-B Fluorine-containing liquid composite ANJI MICROELECTRONICS SHANGHAI 2013-10-02 CN disclosed
CN-102827708-A Plasma etching residue cleaning fluid ANJI MICROELECTRONICS CO LTD 2012-12-19 CN disclosed
CN-102827707-A Plasma etching residue cleaning fluid ANJI MICROELECTRONICS TECHNOLOGY SHANGHAI CO LTD 2012-12-19 CN disclosed
CN-102051281-A Fluorine-containing liquid composite ANJI MICROELECTRONICS SHANGHAI 2011-05-11 CN disclosed
CN-1244316-C Absorbent article with barrier sheet to prevent migration of skin care composition PROCTER & GAMBLE (US) 2006-03-08 CN disclosed
CN-1380824-A Absorbent article having barrier sheet against migration of skin care composition PROCTER & GAMBLE (US) 2002-11-20 CN disclosed
CN-1379688-A Absorbent article with skin care composition PROCTER & GAMBLE (US) 2002-11-13 CN disclosed
CN-1300223-A Disposable absorbent article having a skin care composition containing an enzyme inhibitor PROCTER & GAMBLE (US) 2001-06-20 CN disclosed
US-5830912-A Derivatives of 6,8-difluoro-7-hydroxycoumarin MOLECULAR PROBES, INC. (US) 1998-11-03 US disclosed
US-5446131-A Polypeptides or cylic polypeptide; therapeutic and prophylactic; inhibit thrombin-induced platelet aggregation BIOGEN, INC. (US) 1995-08-29 US disclosed