SCHEMBL754131

SCHEMBL754131

CC(=O)NC(O)(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.47
SRC P12931 1/20 0.47
ELANE P08246 1/20 0.41
ALDH1A1 P00352 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CES2 O00748 1/20 0.39
MAPT P10636 2/20 0.39
KCNN4 O15554 1/20 0.39
CACNA1B Q00975 1/20 0.39
APBA1 Q02410 1/20 0.39
TSHR P16473 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
HSD17B10 Q99714 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1252890 0.85 CES1 (0.46) CES1SRCALDH1A1CES2MAPT
SCHEMBL6438562 0.83 CES1 (0.42) CES1SRCELANEALDH1A1CES2
SCHEMBL27392862 0.83 KCNN4 (0.42) ELANEALDH1A1L3MBTL1MAPTKCNN4
SCHEMBL1395461 0.81 CES1 (0.50) CES1SRCALDH1A1CES2MAPT
SCHEMBL5843722 0.81 ALDH1A1 (0.44) CES1SRCALDH1A1L3MBTL1MAPT
SCHEMBL6253264 0.79 CES1 (0.41) CES1SRCALDH1A1L3MBTL1MAPT
SCHEMBL6447132 0.78 ALDH1A1 (0.45) CES1SRCALDH1A1TSHRPOLB
SCHEMBL5483963 0.78 CES1 (0.46) CES1SRCALDH1A1L3MBTL1CES2
SCHEMBL4769359 0.77 KCNN4 (0.48) CES1SRCALDH1A1L3MBTL1CES2
SCHEMBL5928512 0.76 CES1 (0.45) CES1SRCALDH1A1KCNN4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210332120-A1 TRISPECIFIC ANTIBODIES AGAINST IL-17A, IL-17F AND OTHER PRO-INFLAMMATORY MOLECULE JOINT STOCK COMPANY "BIOCAD" (RU) 2021-10-28 US disclosed
US-11136408-B2 Anti-PD-1 antibodies, method for producing same and method for using same CLOSED JOINT-STOCK COMPANY "BIOCAD" (RU) 2021-10-05 US disclosed
US-10450376-B2 Anti-MET antibodies and compositions SYMPHOGEN A/S (DK) 2019-10-22 US disclosed
EP-3194444-B1 ANTI-MET ANTIBODIES AND COMPOSITIONS SYMPHOGEN AS (DK) 2019-07-10 EP disclosed
EP-3486257-A1 ANTI-PD-1 ANTIBODIES, METHOD FOR PRODUCING SAME AND METHOD FOR USING SAME Joint Stock Company "Biocad" (RU) 2019-05-22 EP disclosed
US-20190127478-A1 ANTI-PD-1 ANTIBODIES, METHOD FOR PRODUCING SAME AND METHOD FOR USING SAME CLOSED JOINT-STOCK COMPANY "BIOCAD" (RU) 2019-05-02 US disclosed
EP-3431501-A1 ANTI NOTCH-1 ANTIBODIES Pfizer Inc (US) 2019-01-23 EP disclosed
CN-109071956-A Composition for thermoplastic elastomer and its manufacturing method and elastomer molded body JXTG能源株式会社 2018-12-21 CN disclosed
US-20180327500-A1 ANTI-MET ANTIBODIES AND COMPOSITIONS LES LABORATOIRES SERVIER (FR) 2018-11-15 US disclosed
CN-108779280-A Composition for foam, process for producing the same, and foam molded article JXTG能源株式会社 2018-11-09 CN disclosed
EP-1291714-A1 An aqueous thermally bleachable composition useful in a photothermographic element EASTMAN KODAK COMPANY (US) 2003-03-12 EP disclosed
US-6451516-B1 AMINOPYRIDINIUM DYE WITH METHIN LINKAGE TERMINATED BY A HETEROCVYCLIC NUCLEUS AS FOUND IN CYANINE DYES EASTMAN KODAK COMPANY 2002-09-17 US disclosed
WO-2002011900-A1 EXPANDABLE GRAPHITE AND METHOD GRAFTECH INC. (US) 2002-02-14 WO disclosed
EP-0814374-A2 Stabilized heat-sensitive imaging material LABELON CORPORATION (US) 1997-12-29 EP disclosed
US-5672560-A PHOSPHATE LABELON CORPORATION (US) 1997-09-30 US disclosed
EP-0679264-A4 1995-11-29 EP disclosed
EP-0679264-A1 THERMAL IMAGING MATERIAL AND PREPARATION LABELON CORPORATION (US) 1995-11-02 EP disclosed
US-5424182-A Mixture of a silver salt of an organic acid, reducing agents, toner and carrier LABELON CORPORATION (US) 1995-06-13 US disclosed
WO-1994016361-A1 THERMAL IMAGING MATERIAL AND PREPARATION LABELON CORPORATION (US) 1994-07-21 WO disclosed
US-4272106-A TRANSPARENT DYE LAYER WHICH CAN UNDERGO COLOR SHIFT IN RESPONSE TO DEVELOPER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-06-09 US disclosed