Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL754131 | 0.81 | CES1 (0.47) | CES1SRCKCNN4TSHRHDAC3 | |
| SCHEMBL1252890 | 0.81 | CES1 (0.46) | CES1SRCKCNN4TSHRHDAC3 | |
| SCHEMBL5483963 | 0.81 | CES1 (0.46) | CES1SRCKCNN4TSHRHDAC3 | |
| SCHEMBL4769359 | 0.80 | KCNN4 (0.48) | CES1SRCKCNN4TSHRHDAC3 | |
| SCHEMBL5928512 | 0.79 | CES1 (0.45) | CES1SRCKCNN4TSHRHDAC3 | |
| SCHEMBL27843769 | 0.78 | CES1 (0.52) | CES1SRCKCNN4TSHRHDAC3 | |
| SCHEMBL28180738 | 0.78 | SRC (0.55) | CES1SRCTSHRHDAC3HDAC1 | |
| SCHEMBL5843722 | 0.78 | ALDH1A1 (0.44) | CES1SRCKCNN4ALDH1A1RAB9A | |
| Dimethylamine SCHEMBL6328605 | 0.77 | CES1 (0.50) | CES1SRCKCNN4TSHRHDAC3 | |
| SCHEMBL11667577 | 0.77 | CES1 (0.42) | CES1SRCKCNN4TSHRHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8444954-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2013-05-21 | — | — | US | disclosed |
| US-8420050-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2013-04-16 | — | — | US | disclosed |
| US-8420053-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2013-04-16 | — | — | US | disclosed |
| US-20120009122-A1 | GASTRIN RELEASING PEPTIDE COMPOUNDS | BRACCO IMAGING S.P.A. (IT) | 2012-01-12 | — | — | US | disclosed |
| US-20110250133-A1 | GASTRIN RELEASING PEPTIDE COMPOUNDS | BRACCO IMAGING S.P.A. (IT) | 2011-10-13 | — | — | US | disclosed |
| US-7922998-B2 | bombesin, derivatives and/or analogues capable of complexing metal ions, radionuclides or optical labels, for use in radiotherapy | BRACCO IMAGING S.P.A. (IT) | 2011-04-12 | — | — | US | disclosed |
| US-20110052491-A1 | GASTRIN RELEASING PEPTIDE COMPOUNDS | BRACCO IMAGING S.P.A. (IT) | 2011-03-03 | — | — | US | disclosed |
| US-20100113549-A1 | PYRROLIDINE COMPOUNDS | ISIS INNOVATION LTD. (GB) | 2010-05-06 | — | — | US | disclosed |
| US-20090175786-A1 | Gastrin Releasing Peptide Compounds | BRACCO IMAGING S.P.A. (IT) | 2009-07-09 | — | — | US | disclosed |
| US-20080008649-A1 | Gastrin Releasing Peptide Compounds | BRACCO IMAGING S.P.A. (IT) | 2008-01-10 | — | — | US | disclosed |
| US-20060018830-A1 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2006-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090175786-A1 | Gastrin Releasing Peptide Compounds | GRPR, SSTR5, GIPR | CES1 4247/4885SRC 2068/4885KCNN4 2542/4885 |
| US-20080008649-A1 | Gastrin Releasing Peptide Compounds | GRPR, SSTR5, GIPR | CES1 4247/4885SRC 2068/4885KCNN4 2542/4885 |
| US-20060018830-A1 | Gastrin releasing peptide compounds | GRPR, GIPR, CCKBR | CES1 4348/4885SRC 2495/4885KCNN4 2142/4885 |
| US-20120009122-A1 | GASTRIN RELEASING PEPTIDE COMPOUNDS | GRPR, GIPR, CCKBR | CES1 4348/4885SRC 2495/4885KCNN4 2142/4885 |
| US-20110250133-A1 | GASTRIN RELEASING PEPTIDE COMPOUNDS | GRPR, GIPR, GHRHR | CES1 3966/4885SRC 3548/4885KCNN4 4329/4885 |
| US-20110052491-A1 | GASTRIN RELEASING PEPTIDE COMPOUNDS | GRPR, GIPR, CCKBR | CES1 4792/4885SRC 3830/4885KCNN4 1294/4885 |
| US-20100113549-A1 | PYRROLIDINE COMPOUNDS | PYCR1, PAH, DHPS | CES1 3025/4885SRC 4551/4885KCNN4 2358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.