SCHEMBL6253344

SCHEMBL6253344

CCCC1=CC(CCc2ccccc2)=CC1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.37
AOC3 Q16853 2/20 0.37
SIGMAR1 Q99720 4/20 0.36
MEN1 O00255 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
TP53 P04637 1/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
KCNH2 Q12809 1/20 0.34
SLC6A3 Q01959 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6251692 0.90 SIGMAR1 (0.40) SIGMAR1KMT2AKCNH2SLC6A3
SCHEMBL6253082 0.88 TP53 (0.40) TAAR1AOC3SIGMAR1TP53MAOA
SCHEMBL6253565 0.86 CALM1 (0.37) TAAR1AOC3SIGMAR1MEN1RAB9A
SCHEMBL6053802 0.81
SCHEMBL6254800 0.73 MAOA (0.38) TAAR1AOC3MAOAMAOBKCNH2
SCHEMBL6252469 0.71 HPGD (0.33) RAB9A
SCHEMBL6546791 0.70 MAOA (0.56) TAAR1SIGMAR1TP53MAOAMAOB
SCHEMBL40575 0.70
Benzene SCHEMBL28308118 0.70 TP53 (0.58) TAAR1AOC3SIGMAR1TP53KCNH2
Butane SCHEMBL6866259 0.70 TP53 (0.58) TAAR1AOC3SIGMAR1TP53MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0926150-B1 Production of alkali metal cyclopentadienylides and production of dihalobis(eta-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylides HONSHU CHEMICAL IND (JP) 2005-09-07 EP disclosed
US-6046346-A Production of alkali metal cyclopentadienylide and production of dihalobis (η-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylide HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2000-04-04 US disclosed
EP-0926150-A2 Production of alkali metal cyclopentadienylide and production of dihalobis(eta-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylide Honshu Chemical Industry Co. Ltd. (JP) 1999-06-30 EP disclosed