Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B | P18089 | 6/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6253700 | 1.00 | ADRA2B (0.34) | ADRA2BADRA2CADRA2ACNR2HTR1A | |
| SCHEMBL5590258 | 0.79 | POLB (0.39) | ADRA2BADRA2CADRA2ANISCHMEN1 | |
| SCHEMBL5590260 | 0.79 | POLB (0.39) | ADRA2BADRA2CADRA2ANISCHMEN1 | |
| SCHEMBL5588477 | 0.77 | POLB (0.38) | ADRA2BADRA2CADRA2ANISCHMEN1 | |
| SCHEMBL6254252 | 0.77 | CNR2 (0.34) | CNR2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6254250 | 0.77 | CNR2 (0.34) | CNR2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6257035 | 0.77 | CNR2 (0.34) | CNR2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6257038 | 0.77 | CNR2 (0.34) | CNR2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6255450 | 0.75 | ADRA2A (0.30) | ADRA2BADRA2CADRA2ACNR2 | |
| SCHEMBL6255455 | 0.75 | ADRA2A (0.30) | ADRA2BADRA2CADRA2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |