Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6255450 | 1.00 | ADRA2A (0.30) | ADRA2AADRA2BADRA2CADRA1DHTR1D | |
| SCHEMBL6253323 | 0.82 | CNR2 (0.31) | CNR2 | |
| SCHEMBL6253318 | 0.82 | CNR2 (0.31) | CNR2 | |
| SCHEMBL6255807 | 0.82 | CNR2 (0.31) | CNR2 | |
| SCHEMBL6255811 | 0.82 | CNR2 (0.31) | CNR2 | |
| SCHEMBL6253702 | 0.75 | ADRA2B (0.34) | ADRA2AADRA2BADRA2CCNR2 | |
| SCHEMBL5596587 | 0.74 | — | — | |
| SCHEMBL6256029 | 0.66 | ADRA2B (0.37) | ADRA2AADRA2BADRA2CCNR2 | |
| SCHEMBL6256030 | 0.66 | ADRA2B (0.37) | ADRA2AADRA2BADRA2CCNR2 | |
| SCHEMBL27582727 | 0.63 | CYP3A4 (0.48) | ADRA2AADRA2BADRA2CHTR1DCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |