Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14257313 | 0.81 | APLNR (0.53) | KDM4EMAPTLMNATSHRHTT | |
| SCHEMBL7745429 | 0.80 | CYP3A4 (0.50) | KDM4EMAPTLMNATSHRHTT | |
| SCHEMBL8581634 | 0.79 | KDM4E (0.54) | KDM4EMAPTLMNATSHRHTT | |
| SCHEMBL10533222 | 0.78 | MAPT (0.49) | KDM4EMAPTLMNAHTTTDP1 | |
| SCHEMBL27606463 | 0.76 | CYP3A4 (0.37) | KDM4EMAPTLMNATSHRHTT | |
| SCHEMBL2788877 | 0.75 | LMNA (0.55) | KDM4EMAPTLMNATSHRHTT | |
| SCHEMBL11581594 | 0.75 | KDM4E (0.54) | KDM4EMAPTLMNATSHRHTT | |
| SCHEMBL194280 | 0.75 | KDM4E (0.54) | KDM4EMAPTLMNATSHRHTT | |
| SCHEMBL30520123 | 0.75 | CYP3A4 (0.47) | KDM4EMAPTTDP1CYP3A4SMN1; SMN2 | |
| SCHEMBL11581590 | 0.75 | KDM4E (0.54) | KDM4EMAPTLMNATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |