Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | CCR1 | P32246 | 4/20 | 0.47 |
| ▸ | CCR8 | P51685 | 4/20 | 0.47 |
| ▸ | CCR5 | P51681 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743453 | 0.84 | APLNR (0.47) | CYP3A4LMNACCR1CCR8CCR5 | |
| SCHEMBL625372 | 0.80 | KDM4E (0.48) | CYP3A4LMNACCR1CCR8CCR5 | |
| SCHEMBL6142388 | 0.77 | LMNA (0.49) | CYP3A4LMNACCR1CCR8CCR5 | |
| SCHEMBL2788877 | 0.73 | LMNA (0.55) | CYP3A4LMNACCR1CCR8CCR5 | |
| SCHEMBL3333505 | 0.73 | CYP3A4 (0.57) | CYP3A4KDM4EMAPTTDP1TSHR | |
| SCHEMBL10533222 | 0.73 | MAPT (0.49) | CYP3A4LMNAKDM4EMAPTHSP90AA1 | |
| SCHEMBL31162473 | 0.72 | CYP3A4 (0.73) | CYP3A4TDP1TSHRALDH1A1 | |
| SCHEMBL110655 | 0.72 | CYP3A4 (0.73) | CYP3A4TDP1TSHRALDH1A1 | |
| SCHEMBL6969195 | 0.72 | MAPT (0.44) | CYP3A4LMNACCR1CCR8CCR5 | |
| SCHEMBL5540582 | 0.72 | LMNA (0.58) | CYP3A4LMNACCR1CCR8CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423724-B1 | PREVENTION, THERAPY DISEASE | THE PROCTER & GAMBLE COMPANY | 2002-07-23 | — | — | US | disclosed |