Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 10/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810364 | 0.81 | EGLN1 (0.41) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7255174 | 0.80 | HDAC3 (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Hydrochloric Acid SCHEMBL27336202 | 0.79 | HDAC3 (0.45) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Methacrylic Acid SCHEMBL28074000 | 0.78 | ACHE (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL29834112 | 0.77 | ACHE (0.54) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4926959 | 0.76 | GAA (0.51) | GLAKMT2AGAA | |
| SCHEMBL27495408 | 0.76 | ACHE (0.45) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL1425763 | 0.76 | GAA (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5165665 | 0.76 | ACHE (0.66) | ACHE | |
| SCHEMBL22369874 | 0.75 | L3MBTL1 (0.39) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005055959-A2 | BULKY MONOMERS LEADING TO RESINS EXHIBITING LOW POLYMERIZATION SHRINKAGE | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-06-23 | — | — | WO | claimed |
| US-20050124721-A1 | Bulky monomers leading to resins exhibiting low polymerization shrinkage | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-06-09 | — | — | US | claimed |
| WO-2005055959-A2 | BULKY MONOMERS LEADING TO RESINS EXHIBITING LOW POLYMERIZATION SHRINKAGE | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-06-23 | — | — | WO | disclosed |
| WO-2005055961-A1 | DENTAL COMPOSITIONS CONTAINING CORE-SHELL POLYMERS WITH LOW MODULUS CORES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-06-23 | — | — | WO | disclosed |
| US-20050124721-A1 | Bulky monomers leading to resins exhibiting low polymerization shrinkage | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-06-09 | — | — | US | disclosed |
| US-20050124762-A1 | Dental compositions containing core-shell polymers with low modulus cores | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124721-A1 | Bulky monomers leading to resins exhibiting low polymerization shrinkage | REV1, TERB1, RAD51 | HDAC3 864/4885HDAC4 1398/4885HDAC1 685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.