Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 9/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6254079 | 0.91 | HPGDS (0.39) | HPGDSLDHACYP11B1CYP11B2BAZ2B | |
| SCHEMBL6256248 | 0.89 | HPGDS (0.41) | HPGDSLDHACYP11B1CYP11B2BAZ2B | |
| SCHEMBL6254179 | 0.85 | HPGDS (0.45) | HPGDSLDHACYP11B1CYP11B2BAZ2B | |
| SCHEMBL7786402 | 0.84 | NPC1 (0.37) | HPGDS | |
| SCHEMBL6252860 | 0.83 | CCR1 (0.44) | LDHACYP11B1CYP11B2BAZ2BCYP3A4 | |
| SCHEMBL6254611 | 0.81 | HPGDS (0.45) | HPGDSLDHACYP11B1CYP11B2BAZ2B | |
| SCHEMBL1054804 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL6254190 | 0.78 | CYP11B1 (0.40) | CYP11B1CYP11B2HSD17B1HSD17B2 | |
| SCHEMBL6254371 | 0.78 | KDM4E (0.42) | — | |
| SCHEMBL6257790 | 0.78 | HPGDS (0.44) | HPGDSLDHACYP11B1CYP11B2BAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143538-B1 | Organic electroluminescent element containing a silacyclopentadiene derivative | CHISSO CORP (JP) | 2005-09-14 | — | — | EP | disclosed |
| EP-1143538-A1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | Chisso Corporation (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6051319-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 2000-04-18 | — | — | US | disclosed |
| US-5986121-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0754691-A2 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1997-01-22 | — | — | EP | disclosed |