SCHEMBL1054804

SCHEMBL1054804

C[Si]1(CC[Si]2(C)C(c3ccccc3)=C(c3ccccc3)C(c3ccccc3)=C2c2ccccc2)C(c2ccccc2)=C(c2ccccc2)C(c2ccccc2)=C1c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
PDE4B Q07343 2/20 0.34
MITF O75030 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TAAR1 Q96RJ0 1/20 0.30
SLC22A2 O15244 1/20 0.30
SLC22A1 O15245 1/20 0.30
SLC22A3 O75751 1/20 0.30
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6257795 0.90 RAB9A (0.39) ALDH1A1MAPT
SCHEMBL6254388 0.89 PTGS1 (0.40) ALDH1A1MAPT
SCHEMBL6254829 0.89 NOTUM (0.48) ALDH1A1MAPTSLC6A4
SCHEMBL6257404 0.86 BACE1 (0.46) ALDH1A1MAPTNPSR1
SCHEMBL6256103 0.84 MAPT (0.35) ALDH1A1PDE4BMAPTHTT
SCHEMBL6253074 0.84 KIF11 (0.53) ALDH1A1
SCHEMBL6256345 0.84 TSHR (0.41) ALDH1A1MAPT
SCHEMBL6257768 0.83 RAB9A (0.41) ALDH1A1MAPTNPSR1
SCHEMBL8333848 0.83 ATM (0.48)
SCHEMBL6257884 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080203406-A1 Layer Assembly for a Light-Emitting Component NOVALDE GMBH (DE) 2008-08-28 US claimed
US-12048175-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2024-07-23 US disclosed
US-12029116-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2024-07-02 US disclosed
US-20240032422-A1 LIGHT-EMITTING MATERIAL, COMPOUND, LONG-PERSISTENT PHOSPHOR AND LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2024-01-25 US disclosed
US-11832516-B2 Light-emitting material, compound, long-persistent phosphor and light-emitting element KYULUX, INC. (JP) 2023-11-28 US disclosed
US-11778904-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2023-10-03 US disclosed
US-11778904-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2023-10-03 US disclosed
US-20230225147-A1 ORGANIC LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-07-13 US disclosed
US-20230209847-A1 ORGANIC LIGHT EMITTING ELEMENT KYULUX, INC. (JP) 2023-06-29 US disclosed
US-20230209847-A1 ORGANIC LIGHT EMITTING ELEMENT KYULUX, INC. (JP) 2023-06-29 US disclosed
EP-1789994-A1 LAYER ARRANGEMENT FOR A LIGHT-EMITTING COMPONENT Novaled AG (DE) 2007-05-30 EP disclosed
US-7195826-B2 Charge transfer compounds; containing organiridium compound TOHOKU PIONEER CORPORATION (JP) 2007-03-27 US disclosed
WO-2006015567-A1 LAYER ARRANGEMENT FOR A LIGHT-EMITTING COMPONENT NOVALED AG (DE) 2006-02-16 WO disclosed
EP-1143538-B1 Organic electroluminescent element containing a silacyclopentadiene derivative CHISSO CORP (JP) 2005-09-14 EP disclosed
US-6902832-B2 Charge-transporting material containing diazapentacene derivative, luminescent material, and organic electroluminescent element employing these CHISSO CORPORATION (JP) 2005-06-07 US disclosed
US-20030099865-A1 Charge-transporting material containing diazapentacene derivative, luminescent material, and organic electroluminescent element employing these CHISSO CORPORATION (JP) 2003-05-29 US disclosed
EP-1143538-A1 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative Chisso Corporation (JP) 2001-10-10 EP disclosed
US-6051319-A Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 2000-04-18 US disclosed
US-5986121-A Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 1999-11-16 US disclosed
EP-0754691-A2 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 1997-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240032422-A1 LIGHT-EMITTING MATERIAL, COMPOUND, LONG-PERSISTENT PHOSPHOR AND LIGHT-EMITTING ELEMENT NR2E3, CRY1, ESR1 ALDH1A1 1064/4885PDE4B 3884/4885MITF 2966/4885
US-12029116-B2 Composition of matter for use in organic light-emitting diodes OPRD1, DRD1, DRD3 ALDH1A1 812/4885PDE4B 4582/4885MITF 2947/4885
US-11778904-B2 Composition of matter for use in organic light-emitting diodes CRY2, SLCO1B3, NDUFV3 ALDH1A1 86/4885PDE4B 4279/4885MITF 415/4885
US-11832516-B2 Light-emitting material, compound, long-persistent phosphor and light-emitting element NR2E3, CRY1, ESR1 ALDH1A1 1064/4885PDE4B 3884/4885MITF 2966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.