SCHEMBL6254546

SCHEMBL6254546

O=C(Oc1cccs1)C(=O)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.43
MMP2 P08253 1/20 0.43
MMP9 P14780 1/20 0.43
MMP12 P39900 1/20 0.43
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
MAPT P10636 2/20 0.35
MEN1 O00255 2/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
KMT2A Q03164 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
DAO P14920 1/20 0.34
HPGDS O60760 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6859151 0.81 MMP1 (0.45) MMP1MMP2MMP9MMP12CES2
SCHEMBL28858282 0.77 MMP1 (0.47) MMP1MMP2MMP9MMP12CES2
SCHEMBL6383050 0.77 MMP1 (0.47) MMP1MMP2MMP9MMP12CES2
SCHEMBL1616681 0.74 MMP1 (0.51) MMP1MMP2MMP9MMP12CES2
SCHEMBL2464311 0.73 MMP1 (0.44) MMP1MMP2MMP9MMP12CES2
SCHEMBL1036006 0.72
SCHEMBL1254648 0.72
SCHEMBL5166429 0.72
SCHEMBL3876236 0.72 CES2 (0.46) CES2CES1MAPTMEN1NPC1
SCHEMBL29173876 0.72 MMP1 (0.46) MMP1MMP2MMP9MMP12CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005061655-A1 USE OF GADOLINIUM(III) CHELATES AS LUMINESCENT MATERIALS IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) BASF AKTIENGESELLSCHAFT (DE) 2005-07-07 WO disclosed