SCHEMBL3876236

SCHEMBL3876236

O=C(OC(=O)c1cccs1)C(=O)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
DAO P14920 1/20 0.44
HTT P42858 1/20 0.44
KMT2A Q03164 6/20 0.42
NPC1 O15118 4/20 0.42
RAB9A P51151 4/20 0.42
MAPT P10636 3/20 0.42
LMNA P02545 2/20 0.42
MEN1 O00255 2/20 0.42
ALDH1A1 P00352 2/20 0.42
POLB P06746 1/20 0.42
HDAC1 Q13547 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
HPGD P15428 2/20 0.41
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2379564 0.83 CES2 (0.48) CES2CES1DAOHTTKMT2A
SCHEMBL10900382 0.81 CES2 (0.47) CES2CES1DAOHTTKMT2A
SCHEMBL3268211 0.80 CES2 (0.62) CES2CES1DAOKMT2ANPC1
SCHEMBL7837835 0.77 RAB9A (0.51) CES2CES1DAOKMT2ANPC1
SCHEMBL17065796 0.77 CES2 (0.65) CES2CES1DAOKMT2ANPC1
SCHEMBL3997033 0.75 CES2 (0.52) CES2CES1DAOHTTKMT2A
Trifluoroacetic Acid SCHEMBL27809835 0.73 KMT2A (0.55) CES2CES1DAOHTTKMT2A
SCHEMBL2915012 0.73 RAB9A (0.54) CES2CES1DAOHTTKMT2A
SCHEMBL6296917 0.73 KMT2A (0.56) CES2CES1DAOKMT2ANPC1
SCHEMBL6254546 0.72 MMP1 (0.43) CES2CES1DAOHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117616032-A Rare earth complex 东曹株式会社 2024-02-27 CN disclosed
EP-2135916-A2 LIGHT-CONVERTING MATERIAL AND A COMPOSITION FOR THE PRODUCTION THEREOF Vorobiev, Victor Andreevich (RU) 2009-12-23 EP disclosed