Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321540 | 0.88 | CES1 (0.49) | CES2CES1PTGS2ALDH1A1LMNA | |
| SCHEMBL10607551 | 0.82 | CES1 (0.46) | CES2CES1PTGS2MAPTALDH1A1 | |
| SCHEMBL19712298 | 0.79 | CES2 (0.43) | CES2CES1PTGS2HDAC3HDAC1 | |
| SCHEMBL27447166 | 0.78 | CES1 (0.47) | CES2CES1MAPTALDH1A1MEN1 | |
| SCHEMBL8994851 | 0.77 | CA1 (0.52) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL10385989 | 0.77 | HDAC3 (0.48) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL9665134 | 0.76 | CES2 (0.49) | CES2CES1LMNA | |
| SCHEMBL14580072 | 0.75 | MAPT (0.58) | CES2CES1NPC1RAB9AMAPT | |
| SCHEMBL26064181 | 0.75 | CES1 (0.49) | CES2CES1PTGS2PPARALMNA | |
| SCHEMBL16062609 | 0.74 | TSHR (0.46) | RAB9AALDH1A1MEN1KMT2ACYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1576061-A2 | TITANIUM DIOXIDE COATED WITH SILICON DIOXIDE | Degussa AG (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004056927-A2 | TITANIUM DIOXIDE COATED WITH SILICON DIOXIDE | DEGUSSA AG (DE) | 2004-07-08 | — | — | WO | disclosed |