Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.52 |
| ▸ | CA2 | P00918 | 6/20 | 0.52 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6613084 | 0.81 | CES2 (0.53) | CA1CA2CES2CES1ALDH1A1 | |
| SCHEMBL2290988 | 0.81 | ALDH1A1 (0.47) | CA2CES2CES1ALDH1A1LMNA | |
| SCHEMBL4808857 | 0.80 | CES1 (0.47) | CES2CES1ALDH1A1LMNAALOX15 | |
| SCHEMBL8214255 | 0.80 | CA12 (0.56) | CA1CA2ALDH1A1MAPK1HDAC3 | |
| SCHEMBL7633456 | 0.78 | MAPT (0.53) | ALDH1A1LMNAGSK3BHDAC3HDAC1 | |
| SCHEMBL6254562 | 0.77 | CES2 (0.53) | CA1CA2CES2CES1ALDH1A1 | |
| SCHEMBL3823617 | 0.77 | CA1 (0.61) | CA1CA2CES2CES1LMNA | |
| SCHEMBL1009355 | 0.77 | CA1 (0.61) | CA1CA2CES2CES1LMNA | |
| SCHEMBL249566 | 0.77 | CA1 (0.61) | CA1CA2CES2CES1LMNA | |
| SCHEMBL1009824 | 0.77 | CA1 (0.61) | CA1CA2CES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727151-A2 | Ingestibles containing substantially tasteless sweetness inhibitors as bitter taste reducers or substantially tasteless bitter inhibitors as sweet taste reducers | BIORESEARCH, INC. (US) | 1996-08-21 | — | — | EP | claimed |
| EP-0485587-A4 | INGESTIBLES CONTAINING SUBSTANTIALLY TASTELESS SWEETNESS INHIBITORS AS BITTER TASTE REDUCERS OR SUBSTANTIALLY TASTELESS BITTER INHIBITORS AS SWEET TASTE REDUCERS | — | 1992-12-02 | — | — | EP | claimed |
| EP-0485587-A1 | INGESTIBLES CONTAINING SUBSTANTIALLY TASTELESS SWEETNESS INHIBITORS AS BITTER TASTE REDUCERS OR SUBSTANTIALLY TASTELESS BITTER INHIBITORS AS SWEET TASTE REDUCERS. | BIORESEARCH INC (US) | 1992-05-20 | — | — | EP | claimed |