Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6254056 | 0.93 | ACHE (0.39) | RAB9ANPC1SMN1; SMN2HPGDTSHR | |
| SCHEMBL6255956 | 0.85 | RAB9A (0.40) | RAB9ANPC1SMN1; SMN2HPGDTSHR | |
| SCHEMBL6253373 | 0.83 | ALDH1A1 (0.35) | SMN1; SMN2HPGDALDH1A1L3MBTL1KMT2A | |
| SCHEMBL6256991 | 0.82 | RAB9A (0.39) | RAB9ANPC1SMN1; SMN2HPGDTSHR | |
| SCHEMBL6257029 | 0.81 | TAAR1 (0.39) | SMN1; SMN2HPGDALDH1A1L3MBTL1MAPT | |
| SCHEMBL6253918 | 0.80 | RAB9A (0.44) | RAB9ANPC1SMN1; SMN2HPGDTSHR | |
| SCHEMBL10018833 | 0.80 | SMN1; SMN2 (0.38) | RAB9ASMN1; SMN2HPGDALDH1A1L3MBTL1 | |
| SCHEMBL6257768 | 0.79 | RAB9A (0.41) | RAB9ANPC1SMN1; SMN2HPGDTSHR | |
| SCHEMBL6656094 | 0.79 | HPGD (0.38) | RAB9ANPC1SMN1; SMN2HPGDTSHR | |
| SCHEMBL6257474 | 0.79 | DYRK1A (0.42) | RAB9ANPC1SMN1; SMN2ALDH1A1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143538-B1 | Organic electroluminescent element containing a silacyclopentadiene derivative | CHISSO CORP (JP) | 2005-09-14 | — | — | EP | disclosed |
| EP-0754691-B1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORP (JP) | 2003-11-19 | — | — | EP | disclosed |
| EP-1143538-A1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | Chisso Corporation (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6051319-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 2000-04-18 | — | — | US | disclosed |