Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | EIF4E | P06730 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27474391 | 0.87 | BCAT2 (0.56) | KDM4EKMT2AEIF4ERECQLBCAT2 | |
| SCHEMBL4881566 | 0.85 | ALDH1A1 (0.58) | P2RX7ALDH1A1POLBPTGER1KDM4E | |
| SCHEMBL3542609 | 0.85 | PTGER1 (0.56) | P2RX7ALDH1A1PTGER1EIF4ETP53 | |
| SCHEMBL31509740 | 0.81 | PPM1B (0.51) | ALDH1A1POLBKDM4EKMT2AGFER | |
| SCHEMBL13522902 | 0.81 | PPM1B (0.51) | ALDH1A1POLBKDM4EKMT2AGFER | |
| SCHEMBL24161843 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KDM4EKMT2ATP53CYP3A4 | |
| SCHEMBL11105555 | 0.79 | MAOB (0.56) | P2RX7MCL1MAPT | |
| SCHEMBL23270907 | 0.79 | CYP3A4 (0.52) | ALDH1A1KDM4EKMT2AGFERRXFP1 | |
| SCHEMBL23354547 | 0.77 | FTO (0.53) | P2RX7ALDH1A1KDM4EEIF4EMYC | |
| SCHEMBL31161066 | 0.77 | CHRM1 (0.53) | P2RX7ALDH1A1EIF4EPDK2ACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005065046-A2 | AN EFFICIENT INDUSTRIAL PROCESS FOR 3-HYDROXY-3-(3’-SULFAMYL-4’-CHLOROPHENYL)PHTALIMIDINE | IPCA LABORATORIES LIMITED (IN) | 2005-07-21 | — | — | WO | disclosed |
| US-4322356-A | Method of preparing substituted phthalides | THE DOW CHEMICAL CO. (US) | 1982-03-30 | — | — | US | disclosed |
| US-4188330-A | Substituted phthalide derivatives | THE DOW CHEMICAL COMPANY (US) | 1980-02-12 | — | — | US | disclosed |