Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6322809 | 0.91 | ADRB1 (0.61) | MEN1KMT2ATAAR1ABCB1MAPK1 | |
| SCHEMBL6255835 | 0.88 | ABCB1 (0.56) | MEN1KMT2ASMN1; SMN2ABCB1MAPT | |
| SCHEMBL6258143 | 0.88 | CASR (0.58) | MEN1KMT2ATAAR1ABCB1MAPT | |
| SCHEMBL6260126 | 0.86 | ABCB1 (0.59) | MEN1KMT2ASMN1; SMN2ABCB1MAPT | |
| SCHEMBL6259862 | 0.86 | ABCB1 (0.58) | ABCB1MAPTMAPK1ADRB1ADRB3 | |
| SCHEMBL6256734 | 0.85 | MEN1 (0.58) | MEN1KMT2ASMN1; SMN2ABCB1MAPT | |
| SCHEMBL6257529 | 0.84 | MEN1 (0.62) | MEN1KMT2ASMN1; SMN2ABCB1MAPT | |
| SCHEMBL6260399 | 0.84 | ADRB1 (0.64) | MEN1KMT2AABCB1MAPTMAPK1 | |
| SCHEMBL6260086 | 0.81 | KDM4E (0.57) | KMT2AABCB1MAPTMAPK1ADRB1 | |
| SCHEMBL8149545 | 0.79 | MEN1 (0.67) | MEN1KMT2ASMN1; SMN2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6962945-B2 | N-aryloxypropanolyl-N′-phenethyl-urea | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-11-08 | — | — | US | claimed |
| US-20050215631-A1 | NOVEL N-ARYLOXYPROPANOLYL-N' - PHENETHYL - UREA | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-09-29 | — | — | US | claimed |
| US-6962945-B2 | N-aryloxypropanolyl-N′-phenethyl-urea | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-11-08 | — | — | US | disclosed |
| US-20050215631-A1 | NOVEL N-ARYLOXYPROPANOLYL-N' - PHENETHYL - UREA | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-09-29 | — | — | US | disclosed |
| WO-2005063699-A1 | N-ARYLOXYPROPANOLYL-N’-PHENETHYL-UREA | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215631-A1 | NOVEL N-ARYLOXYPROPANOLYL-N' - PHENETHYL - UREA | NPY4R, GPR119, MC4R | MEN1 3594/4885KMT2A 1285/4885TAAR1 215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.