Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6260126 | 0.89 | ABCB1 (0.59) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL6322809 | 0.87 | ADRB1 (0.61) | MEN1KMT2AALDH1A1ABCB1CA12 | |
| SCHEMBL6258143 | 0.86 | CASR (0.58) | MEN1KMT2AMAPTALDH1A1ABCB1 | |
| SCHEMBL6255751 | 0.84 | MEN1 (0.61) | MEN1KMT2AMAPTABCB1NPC1 | |
| SCHEMBL6255835 | 0.84 | ABCB1 (0.56) | MEN1KMT2AMAPTALDH1A1ABCB1 | |
| SCHEMBL6260399 | 0.83 | ADRB1 (0.64) | MEN1KMT2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL6259862 | 0.82 | ABCB1 (0.58) | MAPTALDH1A1ABCB1CA12CA1 | |
| SCHEMBL6256734 | 0.81 | MEN1 (0.58) | MEN1KMT2AMAPTNPSR1ABCB1 | |
| SCHEMBL6258812 | 0.81 | MAPT (0.62) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL6260086 | 0.79 | KDM4E (0.57) | KMT2AMAPTALDH1A1ABCB1ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6962945-B2 | N-aryloxypropanolyl-N′-phenethyl-urea | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-11-08 | — | — | US | claimed |
| US-20050215631-A1 | NOVEL N-ARYLOXYPROPANOLYL-N' - PHENETHYL - UREA | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-09-29 | — | — | US | claimed |
| WO-2005063699-A1 | N-ARYLOXYPROPANOLYL-N’-PHENETHYL-UREA | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-07-14 | — | — | WO | claimed |
| US-6962945-B2 | N-aryloxypropanolyl-N′-phenethyl-urea | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-11-08 | — | — | US | disclosed |
| US-20050215631-A1 | NOVEL N-ARYLOXYPROPANOLYL-N' - PHENETHYL - UREA | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-09-29 | — | — | US | disclosed |
| WO-2005063699-A1 | N-ARYLOXYPROPANOLYL-N’-PHENETHYL-UREA | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215631-A1 | NOVEL N-ARYLOXYPROPANOLYL-N' - PHENETHYL - UREA | NPY4R, GPR119, MC4R | MEN1 3594/4885KMT2A 1285/4885MAPT 4471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.