Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 9/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5362814 | 0.89 | KCNB1 (0.42) | KCNA5MT-CO2PTGS2L3MBTL1ERAP2 | |
| SCHEMBL6253331 | 0.87 | KDM4E (0.43) | L3MBTL1ERAP2ERAP1LNPEPALOX15 | |
| SCHEMBL6255884 | 0.82 | ALOX15 (0.39) | KCNA5PTGS2L3MBTL1ALOX15NAAA | |
| SCHEMBL5360875 | 0.77 | PTPN11 (0.44) | ERAP2ERAP1LNPEP | |
| SCHEMBL5362470 | 0.76 | ALDH1A1 (0.45) | NPC1 | |
| SCHEMBL5360954 | 0.76 | ALOX15 (0.42) | ERAP2ERAP1LNPEPALOX15RAB9A | |
| SCHEMBL6256866 | 0.75 | NPC1 (0.39) | PTGS2L3MBTL1ALOX15NAAANPC1 | |
| SCHEMBL5362810 | 0.71 | AOC3 (0.42) | PTGS2ALOX15NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22294656 | 0.70 | LMNA (0.58) | L3MBTL1 | |
| SCHEMBL12352667 | 0.70 | LMNA (0.58) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572629-A1 | COMPOUNDS WHICH MODULATE PPARϝ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2005-09-14 | — | — | EP | claimed |
| WO-2004052840-A1 | COMPOUNDS WHICH MODULATE PPARϜ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-06-24 | — | — | WO | claimed |