Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TTK | P33981 | 2/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.38 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14863636 | 0.76 | L3MBTL1 (0.46) | HDAC6KDM4ECYP3A4TTKAURKB | |
| SCHEMBL14863635 | 0.76 | L3MBTL1 (0.46) | HDAC6KDM4ECYP3A4TTKAURKB | |
| SCHEMBL7149063 | 0.75 | TRPV1 (0.46) | FPR2MEN1KMT2A | |
| SCHEMBL6180760 | 0.74 | NPC1 (0.47) | HDAC6KDM4EKMT2AALDH1A1 | |
| SCHEMBL6993237 | 0.73 | MME (0.46) | KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL6254877 | 0.73 | MME (0.46) | KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL6799200 | 0.69 | MAPT (0.44) | HDAC6KDM4ECYP3A4TTKAURKB | |
| SCHEMBL20217274 | 0.69 | KCNA5 (0.41) | HDAC6KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL10528272 | 0.67 | KMT2A (0.56) | CYP3A4MEN1KMT2AALDH1A1ADORA3 | |
| SCHEMBL6807801 | 0.67 | KCNA5 (0.39) | HDAC6KDM4ECYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1333824-B1 | TREATMENT OF SEXUAL DYSFUNCTION WITH BOMBESIN RECEPTOR ANTAGONISTS | WARNER LAMBERT CO (US) | 2005-09-07 | — | — | EP | disclosed |