Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.46 |
| ▸ | FPR2 | P25090 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.41 |
| ▸ | ELOVL3 | Q9HB03 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6256002 | 0.75 | HDAC6 (0.40) | FPR2MEN1KMT2A | |
| SCHEMBL6184335 | 0.74 | NMBR (0.64) | — | |
| SCHEMBL7149060 | 0.73 | NMBR (0.57) | FPR2 | |
| SCHEMBL14863635 | 0.71 | L3MBTL1 (0.46) | MEN1RAB9AKMT2A | |
| SCHEMBL14863636 | 0.71 | L3MBTL1 (0.46) | MEN1RAB9AKMT2A | |
| SCHEMBL6180760 | 0.70 | NPC1 (0.47) | RAB9AKMT2A | |
| SCHEMBL12377252 | 0.68 | EPHX2 (0.70) | TRPV1FPR2EPHX2MEN1MAPT | |
| SCHEMBL6993237 | 0.67 | MME (0.46) | EPHX2MEN1KMT2A | |
| SCHEMBL6254877 | 0.67 | MME (0.46) | EPHX2MEN1KMT2A | |
| SCHEMBL8308465 | 0.66 | EPHX2 (0.62) | FPR2EPHX2MEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343498-A1 | NOVEL USES OF NON-PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS FOR TREATING ANXIETY AND PANIC DISORDERS | Warner-Lambert Company LLC (US) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002049644-A1 | NOVEL USES OF NON-PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS FOR TREATING ANXIETY AND PANIC DISORDERS | WARNER-LAMBERT COMPANY LLC (US) | 2002-06-27 | — | — | WO | disclosed |