Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6252563 | 0.86 | CYP1A2 (0.51) | HSD17B1HSD17B2GSTP1CYP1A2SMN1; SMN2 | |
| SCHEMBL6257971 | 0.85 | CYP2A6 (0.44) | HSD17B1HSD17B2ESR1ESR2GSTP1 | |
| SCHEMBL6254053 | 0.85 | CYP11B2 (0.54) | HSD17B1HSD17B2GSTP1CYP1A2SMN1; SMN2 | |
| SCHEMBL6252789 | 0.84 | HSD17B1 (0.40) | HSD17B1HSD17B2CYP1A1CYP1B1ESR1 | |
| SCHEMBL6252101 | 0.83 | CYP1A1 (0.43) | HSD17B1HSD17B2CYP1A1CYP1B1CYP1A2 | |
| SCHEMBL6254045 | 0.83 | HSD17B1 (0.39) | HSD17B1HSD17B2CYP1A1CYP1B1ESR1 | |
| SCHEMBL6252650 | 0.82 | CYP1A1 (0.45) | HSD17B1HSD17B2CYP1A1CYP1B1CYP1A2 | |
| SCHEMBL6253440 | 0.82 | PRKCZ (0.46) | CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6254105 | 0.82 | CYP11B2 (0.44) | CYP17A1CYP19A1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL6252623 | 0.82 | CYP1A2 (0.41) | HSD17B1HSD17B2CYP1A1CYP1B1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070207343-A1 | Organic Electroluminescent Device | IDEMITSU KOSAN CO., LTD. (JP) | 2007-09-06 | — | — | US | disclosed |
| EP-1143538-B1 | Organic electroluminescent element containing a silacyclopentadiene derivative | CHISSO CORP (JP) | 2005-09-14 | — | — | EP | disclosed |
| EP-0754691-B1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORP (JP) | 2003-11-19 | — | — | EP | disclosed |
| EP-1143538-A1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | Chisso Corporation (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6051319-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 2000-04-18 | — | — | US | disclosed |
| US-5986121-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0754691-A2 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1997-01-22 | — | — | EP | disclosed |