SCHEMBL6256646

SCHEMBL6256646

CC(C)(C)c1ccccc1S.[Au]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
TDP1 Q9NUW8 2/20 0.48
TSHR P16473 1/20 0.48
CA2 P00918 1/20 0.44
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
KIF11 P52732 1/20 0.36
NPSR1 Q6W5P4 1/20 0.32
MAPT P10636 3/20 0.32
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
ATM Q13315 1/20 0.32
ALOX12 P18054 2/20 0.31
HDAC8 Q9BY41 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL732202 0.97 ALDH1A1 (0.50) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL30772132 0.97 ALDH1A1 (0.50) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL22367879 0.95 ALDH1A1 (0.48) ALDH1A1TDP1TSHRCA2GABRA1
Water SCHEMBL9956053 0.95 ALDH1A1 (0.48) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL27669481 0.90 ALDH1A1 (0.44) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL9396200 0.81 ALDH1A1 (0.39) ALDH1A1TDP1TSHRCA2GABRA1
Tromethamine SCHEMBL6864022 0.80 ALDH1A1 (0.41) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL28696471 0.78 ALDH1A1 (0.43) ALDH1A1TDP1TSHRCA2GABRA1
Trifluoromethanesulfonic Acid SCHEMBL4225729 0.78 TSHR (0.44) ALDH1A1TDP1TSHRCA2CYP1A2
SCHEMBL5983424 0.77 ALDH1A1 (0.36) ALDH1A1TDP1TSHRCA2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005052071-A1 DIGITAL PRINTING INK COMPOSITION JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2005-06-09 WO disclosed