Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 5/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5403694 | 1.00 | PTGS2 (0.48) | PTGS2PRMT6BCL2EPHX2CYP3A4 | |
| SCHEMBL3949412 | 0.90 | PRMT6 (0.43) | PTGS2PRMT6BCL2EPHX2CYP3A4 | |
| SCHEMBL5394154 | 0.84 | PTGS2 (0.42) | PTGS2BCL2FFAR1AOC3PPARG | |
| SCHEMBL5399548 | 0.79 | PPARG (0.55) | PPARGPPARA | |
| SCHEMBL5399556 | 0.79 | PPARG (0.55) | PPARGPPARA | |
| SCHEMBL6252542 | 0.78 | RXRA (0.36) | PTGS2CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL5390373 | 0.78 | RXRA (0.36) | PTGS2CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL5394147 | 0.77 | AOC3 (0.47) | PTGS2AOC3 | |
| SCHEMBL3950853 | 0.74 | PRMT6 (0.45) | PRMT6EPHX2FFAR1HTR7PPARG | |
| SCHEMBL1252083 | 0.71 | PRMT6 (0.73) | PRMT6EPHX2CYP3A4FFAR1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567509-A2 | BIPHENYL COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048351-A2 | BIPHENYL COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-06-10 | — | — | WO | disclosed |