Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6252719 | 1.00 | MAPK1 (0.39) | MAPK1ATMLMNASMN1; SMN2TP53 | |
| SCHEMBL5796714 | 0.87 | MAPK1 (0.38) | MAPK1ATMLMNASMN1; SMN2TP53 | |
| SCHEMBL6255179 | 0.86 | MAPK1 (0.38) | MAPK1ATMLMNASMN1; SMN2TP53 | |
| SCHEMBL3960378 | 0.80 | ATM (0.42) | MAPK1ATMCTSKCTSSCTSL | |
| SCHEMBL3962685 | 0.80 | ATM (0.42) | MAPK1ATMCTSKCTSSCTSL | |
| SCHEMBL7009702 | 0.79 | KMO (0.44) | ATMLMNASMN1; SMN2TP53GFER | |
| SCHEMBL6254005 | 0.76 | ATM (0.41) | MAPK1ATMLMNASMN1; SMN2TP53 | |
| SCHEMBL7008755 | 0.76 | CA1 (0.46) | ATMLMNACTSKCTSSCTSL | |
| SCHEMBL6250919 | 0.76 | ATM (0.41) | MAPK1ATMLMNASMN1; SMN2TP53 | |
| SCHEMBL6252579 | 0.75 | ATM (0.40) | MAPK1ATMLMNASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005053688-A1 | SUBSTITUTED FURO[2,3-G] INDAZOLES FOR THE TREATMENT OF GLAUCOMA | ALCON, INC. (CH) | 2005-06-16 | — | — | WO | disclosed |