Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10018832 | 0.87 | ALDH1A1 (0.43) | PTGS2ALOX5MAPT | |
| SCHEMBL81272 | 0.87 | ALDH1A1 (0.40) | PTGS2KMT2AMAPT | |
| SCHEMBL6254388 | 0.83 | PTGS1 (0.40) | PTGS1PTGS2ACHENFE2L2ADORA1 | |
| SCHEMBL6253450 | 0.82 | PTGS1 (0.39) | PTGS1PTGS2ACHEADORA1MAPK14 | |
| SCHEMBL6257956 | 0.82 | HPGD (0.42) | ACHEMEN1KMT2APOLBALDH1A3 | |
| SCHEMBL18289681 | 0.82 | HPGD (0.42) | ACHEMEN1KMT2APOLBALDH1A3 | |
| SCHEMBL6253617 | 0.81 | TAAR1 (0.40) | ACHENFE2L2ADORA1ADORA2A | |
| SCHEMBL6257061 | 0.80 | SMN1; SMN2 (0.47) | ACHEMEN1KMT2AMAPT | |
| SCHEMBL6256567 | 0.79 | PTGS1 (0.40) | PTGS1PTGS2ACHEADORA1MAPK14 | |
| SCHEMBL7120750 | 0.79 | KIF11 (0.59) | PTGS1PTGS2MAPK14MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143538-B1 | Organic electroluminescent element containing a silacyclopentadiene derivative | CHISSO CORP (JP) | 2005-09-14 | — | — | EP | disclosed |
| EP-0754691-B1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORP (JP) | 2003-11-19 | — | — | EP | disclosed |
| EP-1143538-A1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | Chisso Corporation (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6051319-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 2000-04-18 | — | — | US | disclosed |
| US-5986121-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0754691-A2 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1997-01-22 | — | — | EP | disclosed |