SCHEMBL81272

SCHEMBL81272

C[Si]1(C)C(c2ccccc2)=C(c2ccccc2)C(c2ccccc2)=C1c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
PDE4B Q07343 1/20 0.38
MAPT P10636 3/20 0.33
HTT P42858 2/20 0.33
SLC22A2 O15244 1/20 0.33
SLC22A1 O15245 1/20 0.33
SLC22A3 O75751 1/20 0.33
SLC6A4 P31645 1/20 0.33
MITF O75030 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PTGS2 P35354 2/20 0.32
CDC25A P30304 1/20 0.32
CDC25B P30305 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPK1 P28482 2/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
LMNA P02545 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
HSP90AA1 P07900 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10018832 0.95 ALDH1A1 (0.43) ALDH1A1PDE4BMAPTSLC22A2SLC22A1
SCHEMBL18289681 0.89 HPGD (0.42) ALDH1A1MAPTKMT2ANPC1RAB9A
SCHEMBL6257956 0.89 HPGD (0.42) ALDH1A1MAPTKMT2ANPC1RAB9A
SCHEMBL6256695 0.87 NOTUM (0.54) ALDH1A1MAPTSLC6A4KMT2ANPC1
SCHEMBL6257478 0.87 PTGS1 (0.43) MAPTPTGS2KMT2A
SCHEMBL14413708 0.84 MAOA (0.40) ALDH1A1KMT2ACYP1A2CYP3A4NOTUM
SCHEMBL17678815 0.84 KIF11 (0.41) MAPTNPC1RAB9ALMNATDP1
SCHEMBL13777181 0.84 ACHE (0.36) ALDH1A1MAPTHTTPTGS2MAPK1
SCHEMBL6254417 0.84 NPC1 (0.47) ALDH1A1MAPTNPSR1KMT2ANPC1
SCHEMBL13777194 0.84 ACHE (0.36) ALDH1A1MAPTHTTPTGS2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10444249-B2 Ion sensor JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2019-10-15 US claimed
US-20160169920-A1 ION SENSOR JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2016-06-16 US claimed
EP-3029079-A1 ION SENSOR Japan Science and Technology Agency (JP) 2016-06-08 EP claimed
CN-119431642-A Resin particle composition, detection kit, and method for producing resin particle composition 赛登化学株式会社 2025-02-14 CN disclosed
US-20250043103-A1 RESIN PARTICLE COMPOSITION, TEST KIT, AND MANUFACTURING METHOD OF RESIN PARTICLE COMPOSITION SAIDEN CHEMICAL INDUSTRY CO., LTD. (JP) 2025-02-06 US disclosed
EP-4501971-A1 RESIN PARTICLE COMPOSITION, TEST KIT, AND MANUFACTURING METHOD OF RESIN PARTICLE COMPOSITION Saiden Chemical Industry Co., Ltd. (JP) 2025-02-05 EP disclosed
US-12048175-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2024-07-23 US disclosed
US-12048175-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2024-07-23 US disclosed
US-20240032422-A1 LIGHT-EMITTING MATERIAL, COMPOUND, LONG-PERSISTENT PHOSPHOR AND LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2024-01-25 US disclosed
US-20240032422-A1 LIGHT-EMITTING MATERIAL, COMPOUND, LONG-PERSISTENT PHOSPHOR AND LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2024-01-25 US disclosed
US-11832516-B2 Light-emitting material, compound, long-persistent phosphor and light-emitting element KYULUX, INC. (JP) 2023-11-28 US disclosed
US-20080220407-A1 Fluorescent water-soluble conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2008-09-11 US disclosed
US-7374829-B2 Organic electroluminescent element and full color display KONICA CORPORATION (JP) 2008-05-20 US disclosed
US-20060240565-A1 Environment sensor and conjugated polyene for manufacturing environment sensors HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY, THE (HK) 2006-10-26 US disclosed
EP-1143538-B1 Organic electroluminescent element containing a silacyclopentadiene derivative CHISSO CORP (JP) 2005-09-14 EP disclosed
EP-0754691-B1 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORP (JP) 2003-11-19 EP disclosed
EP-1143538-A1 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative Chisso Corporation (JP) 2001-10-10 EP disclosed
US-6051319-A Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 2000-04-18 US disclosed
US-5986121-A Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 1999-11-16 US disclosed
EP-0754691-A2 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 1997-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240032422-A1 LIGHT-EMITTING MATERIAL, COMPOUND, LONG-PERSISTENT PHOSPHOR AND LIGHT-EMITTING ELEMENT NR2E3, CRY1, ESR1 ALDH1A1 1064/4885PDE4B 3884/4885MAPT 1967/4885
US-20160169920-A1 ION SENSOR ORAI1, CACNA1E, NCS1 ALDH1A1 4261/4885PDE4B 3532/4885MAPT 1581/4885
US-11832516-B2 Light-emitting material, compound, long-persistent phosphor and light-emitting element NR2E3, CRY1, ESR1 ALDH1A1 1064/4885PDE4B 3884/4885MAPT 1967/4885
US-20080220407-A1 Fluorescent water-soluble conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same FUS, CD63, EPCAM ALDH1A1 1173/4885PDE4B 4600/4885MAPT 580/4885
US-10444249-B2 Ion sensor ORAI1, NCS1, CACNA1E ALDH1A1 4171/4885PDE4B 3995/4885MAPT 1371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.