Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | TDO2 | P48775 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11719990 | 0.84 | TSHR (0.44) | CYP3A4ALDH1A1MAPTCYP2C9TSHR | |
| SCHEMBL953105 | 0.83 | CES2 (0.40) | MC4RTSHRL3MBTL1CES2CES1 | |
| SCHEMBL28268337 | 0.80 | L3MBTL1 (0.36) | MC4RCYP3A4MEN1ALDH1A1MAPT | |
| SCHEMBL2194908 | 0.79 | CYP3A4 (0.41) | CYP3A4MEN1ALDH1A1MAPTCYP2C9 | |
| SCHEMBL8377391 | 0.78 | CYP3A4 (0.40) | MC4RCYP3A4MEN1ALDH1A1MAPT | |
| SCHEMBL781961 | 0.77 | TSHR (0.40) | MC4RCYP3A4MEN1ALDH1A1MAPT | |
| SCHEMBL21910179 | 0.77 | IDO1 (0.47) | MC4RCYP3A4MEN1ALDH1A1MAPT | |
| SCHEMBL2554033 | 0.76 | MC4R (0.39) | MC4RCES2CES1ACHE | |
| SCHEMBL20807370 | 0.76 | TSHR (0.59) | MC4RCYP3A4MEN1ALDH1A1MAPT | |
| SCHEMBL778759 | 0.76 | TSHR (0.59) | MC4RCYP3A4MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050215435-A1 | Phenylalanine derivatives as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2005-09-29 | — | — | US | disclosed |
| EP-1474381-B1 | PHENYLALANINE DERIVATIVES AS HERBICIDES | BASF AG (DE) | 2005-09-28 | — | — | EP | disclosed |
| EP-1474381-A1 | PHENYLALANINE DERIVATIVES AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003066576-A1 | PHENYLALANINE DERIVATIVES AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-14 | — | — | WO | disclosed |
| EP-1218370-A2 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | Aventis Pharma S.A. (FR) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001025227-A2 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215435-A1 | Phenylalanine derivatives as herbicides | PAH, DDT, HPD | MC4R 526/4885CYP3A4 315/4885MEN1 4688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.