Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 9/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21959040 | 0.85 | FDPS (0.54) | FDPSPDE3ALMNAGABBR2GABBR1 | |
| SCHEMBL1130279 | 0.75 | FDPS (0.43) | FDPSPDE3ALMNAGABBR2GABBR1 | |
| SCHEMBL5277592 | 0.73 | FDPS (0.58) | FDPSPDE3ALMNAGABBR2GABBR1 | |
| SCHEMBL17499972 | 0.70 | FDPS (0.54) | FDPSPDE3ALMNAGABBR2GABBR1 | |
| SCHEMBL8050464 | 0.68 | FDPS (0.68) | FDPSPDE3ALMNAGABBR2GABBR1 | |
| SCHEMBL8050321 | 0.67 | FDPS (0.61) | FDPSPDE3ALMNAGABBR2GABBR1 | |
| SCHEMBL177948 | 0.67 | FDPS (0.66) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL27172691 | 0.66 | FDPS (0.44) | FDPSPDE3ALMNAGABBR2GABBR1 | |
| SCHEMBL17915728 | 0.65 | FDPS (0.58) | FDPSPDE3ALMNAGABBR2GABBR1 | |
| SCHEMBL4276586 | 0.64 | FDPS (0.47) | FDPSPDE3ALMNAGABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372669-B1 | COMPOSITION COMPRISING BISPHOSPHONATES FOR PREVENTION AND/OR TREATMENT OF METABOLIC DISEASES OF BONES, PROCESS FOR PREPARING SUCH COMPOSITION AND USE THEREOF | GADOR SA (AR) | 2005-06-15 | — | — | EP | claimed |