SCHEMBL177948

SCHEMBL177948

NCCCC(OP(=O)(O)C(O)(CCCN)P(=O)(O)O)(P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.66

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FDPS P14324 16/20 0.66
PDE3A Q14432 2/20 0.66
LMNA P02545 2/20 0.48
ADRB3 P13945 1/20 0.48
PDE4D Q08499 1/20 0.48
GGPS1 O95749 7/20 0.40
CYP3A4 P08684 1/20 0.33
NFKB1 P19838 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Olpadronic Acid SCHEMBL6439356 0.87 FDPS (0.54) FDPSPDE3ALMNAADRB3PDE4D
SCHEMBL2178802 0.87 FDPS (0.63) FDPSPDE3ALMNAADRB3PDE4D
SCHEMBL6669236 0.84 FDPS (0.63) FDPSPDE3ALMNAADRB3PDE4D
Alendronic Acid SCHEMBL18898 0.80 FDPS (1.00) FDPSPDE3ALMNAADRB3PDE4D
Alendronic Acid SCHEMBL6270347 0.80 FDPS (1.00) FDPSPDE3ALMNAADRB3PDE4D
SCHEMBL8050464 0.80 FDPS (0.68) FDPSPDE3ALMNAADRB3PDE4D
SCHEMBL17499972 0.79 FDPS (0.54) FDPSPDE3ALMNAADRB3PDE4D
Alendronic Acid SCHEMBL19614558 0.78 FDPS (0.95) FDPSPDE3ALMNAADRB3PDE4D
Alendronic Acid SCHEMBL4646147 0.78 FDPS (0.95) FDPSPDE3ALMNAADRB3PDE4D
Alendronic Acid SCHEMBL579001 0.78 FDPS (0.95) FDPSPDE3ALMNAADRB3PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 788 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023090899-A1 METHOD FOR PREPARING MICROPARTICLES CONTAINING POORLY SOLUBLE DRUGS (주)인벤티지랩 2023-05-25 WO claimed
US-12037385-B2 Anti-polyubiquitin antibodies and methods of use GENENTECH, INC. (US) 2024-07-16 US disclosed
US-12030926-B2 Production of heteromultimeric proteins using mammalian cells GENENTECH, INC. (US) 2024-07-09 US disclosed
US-20240200146-A1 DIAGNOSTIC AND THERAPEUTIC METHODS FOR CANCER GENENTECH INC (US) 2024-06-20 US disclosed
US-20240190967-A1 THERAPEUTIC AND DIAGNOSTIC METHODS FOR CANCER GENENTECH INC (US) 2024-06-13 US disclosed
US-20240175088-A1 Methods and Systems for Analyzing Nucleic Acid Molecules THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-05-30 US disclosed
US-20240158513-A1 FC Variants and Methods for Their Production GENENTECH, INC. (US) 2024-05-16 US disclosed
US-20240148760-A1 METHODS AND COMPOSITIONS FOR CANNABINOID-BASED THERAPEUTICS OJAI ENERGETICS PBC 2024-05-09 US disclosed
US-11965215-B2 Methods and systems for analyzing nucleic acid molecules THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-04-23 US disclosed
EP-4334476-A1 METHODS AND SYSTEMS FOR ANALYZING NUCLEIC ACID MOLECULES The Board of Trustees of the Leland Stanford Junior University (US) 2024-03-13 EP disclosed
US-20040043072-A1 Alleviation of upper gastrointestinal irritation WILL JOANNE PATRICIA (US) 2004-03-04 US disclosed
EP-1378234-A1 Effervescent bisphosphonate formulation MERCK & CO. INC. (US) 2004-01-07 EP disclosed
EP-0939624-B1 EFFERVESCENT BISPHOSPHONATE FORMULATION MERCK & CO INC (US) 2003-12-17 EP disclosed
EP-1311213-A1 VAGINAL DELIVERY OF BISPHOSPHONATES UMD, Inc. (US) 2003-05-21 EP disclosed
US-20030003147-A1 Effer-vescent bisphosphonate formulation MERCK & CO., INC. 2003-01-02 US disclosed
WO-2002009631-A1 VAGINAL DELIVERY OF BISPHOSPHONATES UMD, INC. (US) 2002-02-07 WO disclosed
US-20010041165-A1 Effervescent bisphosphonate formulation MERCK & CO., INC. 2001-11-15 US disclosed
EP-1102590-A1 USE OF A NK-1 RECEPTOR ANTAGONIST FOR TREATING OR PREVENTING ABNORMAL BONE RESORPTION MERCK SHARP & DOHME LTD. (GB) 2001-05-30 EP disclosed
WO-2000007598-A1 USE OF A NK-1 RECEPTOR ANTAGONIST FOR TREATING OR PREVENTING ABNORMAL BONE RESORPTION MERCK SHARP & DOHME LIMITED (GB) 2000-02-17 WO disclosed
US-5853759-A Effervescent alendronate formulation MERCK & CO.. INC. (US) 1998-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240148760-A1 METHODS AND COMPOSITIONS FOR CANNABINOID-BASED THERAPEUTICS CNR2, CNR1, FAAH FDPS 1169/4885PDE3A 2026/4885LMNA 2479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.