Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 9/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499972 | 0.84 | FDPS (0.54) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL5277592 | 0.76 | FDPS (0.58) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL27661427 | 0.75 | FDPS (0.37) | FDPSPDE3ALMNABLMSMPD1 | |
| SCHEMBL177948 | 0.73 | FDPS (0.66) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL21959040 | 0.72 | FDPS (0.54) | FDPSPDE3ALMNAADRB3PDE4D | |
| Pyrophosphoric Acid SCHEMBL17311814 | 0.70 | FDPS (0.59) | FDPSPDE3ALMNABLMCYP3A4 | |
| Pyrophosphoric Acid SCHEMBL17311822 | 0.70 | FDPS (0.59) | FDPSPDE3ALMNABLMCYP3A4 | |
| SCHEMBL5459582 | 0.69 | FDPS (0.35) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL5455779 | 0.68 | BTN3A1 (0.42) | FDPSBLMSMPD1TDP1 | |
| SCHEMBL8169756 | 0.68 | ITPR3 (0.53) | LMNABLMCYP3A4NFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150157649-A1 | LONG TERM SUSTAINED RELEASE PHARMACEUTICAL COMPOSITION CONTAINING AQUEOUS SUSPENSION OF BISPHOSPHONATE | INTERNATIONAL MEDICATION SYSTEMS, LIMITED | 2015-06-11 | — | — | US | disclosed |
| US-20150157650-A1 | LONG TERM SUSTAINED RELEASE PHARMACEUTICAL COMPOSITION CONTAINING AQUEOUS SUSPENSION OF BISPHOSPHONATE | INTERNATIONAL MEDICATION SYSTEMS, LIMITED | 2015-06-11 | — | — | US | disclosed |
| US-8974801-B2 | Long term sustained release pharmaceutical composition containing aqueous suspension of bisphosphonate | AMPHASTAR PHARMACEUTICALS INC. (US) | 2015-03-10 | — | — | US | disclosed |
| EP-2548441-B1 | Long term sustained release pharmaceutical composition containing aqueous suspension of bisphosphonate | AMPHASTAR PHARMACEUTICALS INC (US) | 2014-08-27 | — | — | EP | disclosed |
| CN-101616591-B | Long term sustained release pharmaceutical composition containing aqueous suspension of bisphosphonate | AMPHASTAR PHARMACEUTICALS INC | 2014-06-18 | — | — | CN | disclosed |
| EP-2548441-A1 | Long term sustained release pharmaceutical composition containing aqueous suspension of bisphosphonate | Amphastar Pharmaceuticals Incorporation (US) | 2013-01-23 | — | — | EP | disclosed |
| EP-2120585-B1 | LONG TERM SUSTAINED RELEASE PHARMACEUTICAL COMPOSITION CONTAINING AQUEOUS SUSPENSION OF BISPHOSPHONATE | AMPHASTAR PHARMACEUTICALS INC (US) | 2012-10-03 | — | — | EP | disclosed |
| CN-101616591-A | The long term sustained release pharmaceutical composition that comprises the aqueous suspension of bisphosphonate | AMPHASTAR PHARMACEUTICALS INC | 2009-12-30 | — | — | CN | disclosed |
| EP-2120585-A1 | LONG TERM SUSTAINED RELEASE PHARMACEUTICAL COMPOSITION CONTAINING AQUEOUS SUSPENSION OF BISPHOSPHONATE | Amphastar Pharmaceuticals Incorporation (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008085281-A1 | LONG TERM SUSTAINED RELEASE PHARMACEUTICAL COMPOSITION CONTAINING AQUEOUS SUSPENSION OF BISPHOSPHONATE | AMPHASTAR PHARMACEUTICALS, INC. (US) | 2008-07-17 | — | — | WO | disclosed |
| US-20080153784-A1 | LONG TERM SUSTAINED RELEASE PHARMACEUTICAL COMPOSITION CONTAINING AQUEOUS SUSPENSION OF BISPHOSPHONATE | WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153784-A1 | LONG TERM SUSTAINED RELEASE PHARMACEUTICAL COMPOSITION CONTAINING AQUEOUS SUSPENSION OF BISPHOSPHONATE | SOST, PTH1R, BPGM | FDPS 841/4885PDE3A 326/4885LMNA 4276/4885 |
| US-20150157650-A1 | LONG TERM SUSTAINED RELEASE PHARMACEUTICAL COMPOSITION CONTAINING AQUEOUS SUSPENSION OF BISPHOSPHONATE | SOST, PTH1R, BPGM | FDPS 841/4885PDE3A 326/4885LMNA 4276/4885 |
| US-20150157649-A1 | LONG TERM SUSTAINED RELEASE PHARMACEUTICAL COMPOSITION CONTAINING AQUEOUS SUSPENSION OF BISPHOSPHONATE | SOST, PTH1R, BPGM | FDPS 841/4885PDE3A 326/4885LMNA 4276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.