Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | CRHBP | P24387 | 1/20 | 0.74 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL796235 | 0.80 | MAPT (0.81) | NPSR1MAPTCRHBPCRHR2LMNA | |
| SCHEMBL17220216 | 0.73 | MAPT (0.69) | NPSR1MAPTCRHBPCRHR2ALDH1A1 | |
| SCHEMBL13363711 | 0.73 | TDP1 (0.70) | ADORA1ADORA2ATDP1 | |
| SCHEMBL13752166 | 0.73 | MAPT (0.73) | NPSR1MAPTCRHBPCRHR2ALDH1A1 | |
| SCHEMBL6240322 | 0.71 | CTSS (0.64) | ADORA1ADORA2ATDP1 | |
| SCHEMBL19032050 | 0.71 | CFTR (0.59) | NPSR1MAPTCRHBPCRHR2LMNA | |
| SCHEMBL19032109 | 0.69 | CFTR (0.61) | NPSR1MAPTCRHBPCRHR2ALDH1A1 | |
| SCHEMBL148052 | 0.68 | MAPT (0.62) | NPSR1MAPTCRHBPCRHR2ALDH1A1 | |
| SCHEMBL9004372 | 0.68 | MAPT (0.50) | NPSR1MAPTCRHBPCRHR2ALDH1A1 | |
| SCHEMBL9004420 | 0.67 | MAPT (0.49) | NPSR1MAPTCRHBPCRHR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011703-A1 | 2-CYANO-1,3,5-TRIAZINE-4,6-DIAMINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |