Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17695756 | 0.86 | ALDH1A1 (0.50) | ALDH1A1CYP1A2TSHRMEN1KMT2A | |
| SCHEMBL30331074 | 0.85 | CYP1A2 (0.54) | ALDH1A1CYP1A2TSHRMEN1KMT2A | |
| SCHEMBL11461676 | 0.85 | CYP1A2 (0.54) | ALDH1A1CYP1A2TSHRMEN1KMT2A | |
| SCHEMBL10400828 | 0.85 | ALDH1A1 (0.49) | ALDH1A1CYP1A2TSHRMEN1KMT2A | |
| SCHEMBL7153686 | 0.84 | CYP1A2 (0.53) | ALDH1A1CYP1A2TSHRMEN1KMT2A | |
| SCHEMBL267829 | 0.84 | CYP1A2 (0.53) | ALDH1A1CYP1A2TSHRMEN1KMT2A | |
| SCHEMBL12232402 | 0.84 | CYP1A2 (0.53) | ALDH1A1CYP1A2TSHRMEN1KMT2A | |
| SCHEMBL31145677 | 0.84 | CYP1A2 (0.53) | ALDH1A1CYP1A2TSHRMEN1KMT2A | |
| SCHEMBL14599491 | 0.84 | CYP1A2 (0.53) | ALDH1A1CYP1A2TSHRMEN1KMT2A | |
| SCHEMBL1123533 | 0.83 | ALDH1A1 (0.48) | ALDH1A1CYP1A2TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397737-A2 | LOW VISCOSITY LOW VOLATILITY LUBRICATING OIL BASE STOCKS AND METHODS OF USE THEREOF | ExxonMobil Research and Engineering Company (US) | 2018-11-07 | — | — | EP | disclosed |
| US-10077409-B2 | Low viscosity low volatility lubricating oil base stocks and methods of use thereof | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2018-09-18 | — | — | US | disclosed |
| EP-2821792-B1 | Whole proteome tiling microarrays | HOFFMANN LA ROCHE (CH) | 2017-09-13 | — | — | EP | disclosed |
| WO-2017116899-A2 | LOW VISCOSITY LOW VOLATILITY LUBRICATING OIL BASE STOCKS AND METHODS OF USE THEREOF | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2017-07-06 | — | — | WO | disclosed |
| US-20170183595-A1 | LOW VISCOSITY LOW VOLATILITY LUBRICATING OIL BASE STOCKS AND METHODS OF USE THEREOF | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2017-06-29 | — | — | US | disclosed |
| EP-2686351-B1 | METHODS FOR SYNTHESIS OF AN OLIGOPEPTIDE MICROARRAY | ROCHE DIAGNOSTICS GMBH (DE) | 2017-06-28 | — | — | EP | disclosed |
| US-9346892-B2 | Methods for synthesis of an oligopeptide microarray | ROCHE NIMBLE GEN, INC. (US) | 2016-05-24 | — | — | US | disclosed |
| US-20150377898-A1 | WHOLE PROTEOME TILING MICROARRAYS | ROCHE NIMBLEGEN INC (US) | 2015-12-31 | — | — | US | disclosed |
| EP-2827151-A1 | Whole proteome tiling microarrays | F. Hoffmann-La Roche AG (CH) | 2015-01-21 | — | — | EP | disclosed |
| EP-2821792-A1 | Whole proteome tiling microarrays | F. Hoffmann-La Roche AG (CH) | 2015-01-07 | — | — | EP | disclosed |
| US-8658572-B2 | Whole proteome tiling microarrays | ROCHE NIMBLEGEN, INC. (US) | 2014-02-25 | — | — | US | disclosed |
| CN-102050741-B | Process for producing nitroalcohols | ROHM & HAAS | 2014-02-12 | — | — | CN | disclosed |
| US-20120245057-A1 | WHOLE PROTEOME TILING MICROARRAYS | Roche Sequencing Solutions, Inc. | 2012-09-27 | — | — | US | disclosed |
| US-20120238477-A1 | METHODS FOR SYNTHESIS OF AN OLIGOPEPTIDE MICROARRAY | Roche Sequencing Solutions, Inc. | 2012-09-20 | — | — | US | disclosed |
| CN-102050741-A | Process for producing nitroalcohols | ROHM & HAAS | 2011-05-11 | — | — | CN | disclosed |
| WO-2005073389-A1 | METHOD FOR PRODUCING β-HYDROXY NITRO COMPOUNDS MADE FROM ALDEHYDES AND NITROALKANES WHILE USING A HYDROXY NITRILE LYASE | ANGEWANDTE BIOKATALYSE-KOMPETENZZENTRUM GMBH (AT) | 2005-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10077409-B2 | Low viscosity low volatility lubricating oil base stocks and methods of use thereof | F12, POLH, STK33 | ALDH1A1 2324/4885CYP1A2 3719/4885TSHR 2839/4885 |
| US-20170183595-A1 | LOW VISCOSITY LOW VOLATILITY LUBRICATING OIL BASE STOCKS AND METHODS OF USE THEREOF | F12, POLH, STK33 | ALDH1A1 2324/4885CYP1A2 3719/4885TSHR 2839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.