Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11004820 | 0.85 | CYP2A6 (0.39) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL5659205 | 0.79 | PTGS2 (0.43) | CD274PDCD1FOLH1PTGS2DPP4 | |
| SCHEMBL5098194 | 0.76 | ALDH1A1 (0.45) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL2701242 | 0.76 | PDCD1 (0.49) | CD274PDCD1TSHRSCN8AFOLH1 | |
| SCHEMBL1024527 | 0.74 | PDCD1 (0.47) | CD274PDCD1KDM4EALOX15FOLH1 | |
| Ammonia Solution, Strong SCHEMBL27731975 | 0.74 | PDCD1 (0.47) | CD274PDCD1TSHRSCN8AFOLH1 | |
| SCHEMBL5907402 | 0.74 | PDCD1 (0.50) | CD274PDCD1KDM4EALDH1A1SCN8A | |
| SCHEMBL10751260 | 0.74 | CD274 (0.56) | CD274PDCD1 | |
| SCHEMBL8903484 | 0.74 | NQO2 (0.55) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL3578553 | 0.73 | LMNA (0.45) | KDM4EUSP2ALDH1A1LMNAMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578716-A1 | DICARBOXYLIC ACID DERIVATIVES AS PPAR-AGONISTS | NOVO NORDISK A/S (DK) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004056740-A1 | DICARBOXYLIC ACID DERIVATIVES AS PPAR-AGONISTS | NOVO NORDISK A/S (DK) | 2004-07-08 | — | — | WO | disclosed |