SCHEMBL625947

SCHEMBL625947

NCC(O)Oc1ccc(N)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.42
ALDH1A1 P00352 4/20 0.42
TSHR P16473 2/20 0.42
CYP3A4 P08684 2/20 0.42
MAPK1 P28482 1/20 0.39
MAOA P21397 3/20 0.37
LOXL2 Q9Y4K0 1/20 0.36
MAPT P10636 5/20 0.35
MAOB P27338 2/20 0.35
TEAD4 Q15561 1/20 0.35
GAA P10253 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
PARP10 Q53GL7 1/20 0.35
RAB9A P51151 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 1/20 0.34
MITF O75030 1/20 0.34
GFER P55789 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27926179 0.98 TDP1 (0.41) TDP1ALDH1A1TSHRCYP3A4MAPK1
Hydrochloric Acid SCHEMBL9771748 0.98 TDP1 (0.41) TDP1ALDH1A1TSHRCYP3A4MAPK1
Sulfuric Acid SCHEMBL4439578 0.91 TSHR (0.39) TDP1ALDH1A1TSHRCYP3A4MAPK1
SCHEMBL109613 0.83 TDP1 (0.42) TDP1ALDH1A1TSHRCYP3A4MAPK1
SCHEMBL28219139 0.83 TAAR1 (0.48) TDP1ALDH1A1TSHRL3MBTL1MEN1
Hydrochloric Acid SCHEMBL18243324 0.82 PDE10A (0.36) TDP1ALDH1A1TSHRCYP3A4MAPK1
Water SCHEMBL9794578 0.81 TDP1 (0.41) TDP1ALDH1A1TSHRCYP3A4MAPK1
SCHEMBL9704893 0.81 TDP1 (0.41) TDP1ALDH1A1TSHRCYP3A4MAPK1
Hydrochloric Acid SCHEMBL9794570 0.81 TDP1 (0.41) TDP1ALDH1A1TSHRCYP3A4MAPK1
SCHEMBL8694787 0.80 LMNA (0.42) ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1674075-B1 Hair colouring process comprising a cleaning step ORÉAL L (FR) 2016-07-20 EP claimed
EP-1037592-B2 NEW DEVELOPER COMBINATIONS FOR OXIDATION COLOURING AGENTS HENKEL AG & CO KGAA (DE) 2015-08-19 EP claimed
EP-1222911-B1 Hair dye composition and process for dyeing human hair KPSS KAO GMBH (DE) 2006-10-25 EP claimed
EP-1674075-A1 Colored hair treating process with a composition comprising a specific non ionic surfactant and use to protect the coloration L'OREAL (FR) 2006-06-28 EP claimed
EP-1674074-A1 Colored hair treating process with a composition comprising a specific non ionic and/or an amphoteric and/or a mild anionic surfactant and use to protect the coloration L'OREAL (FR) 2006-06-28 EP claimed
EP-0988022-B1 HAIR DYE HENKEL KGAA (DE) 2005-09-21 EP claimed
EP-1194116-B1 AGENT FOR DYEING FIBRES CONTAINING KERATIN HENKEL KGAA (DE) 2005-05-04 EP claimed
EP-1002518-B1 Composition for oxidative dyeing of keratinous fibres and dyeing process using same OREAL (FR) 2004-12-08 EP claimed
EP-0835093-B1 HAIR DYE AGENTS WITH AT LEAST ONE CONDITIONER HANS SCHWARZKOPF & HENKEL GMBH (DE) 2004-03-10 EP claimed
EP-0873109-B1 COLORANT FOR PRODUCING METAMERIC EFFECTS ON KERATIN FIBRES WELLA AG (DE) 2004-02-04 EP claimed
EP-0226072-B1 OXIDATION DYE CONTAINING 4-AMINO-2-AMINOMETHYL PHENOL Wella Aktiengesellschaft (DE) 1991-04-10 EP claimed
EP-0252351-B1 5-ALKOXY-2,4-DIAMINO-ALKYLBENZENES AND HAIR DYES CONTAINING SAME Wella Aktiengesellschaft (DE) 1990-09-12 EP claimed
US-4797130-A DYE DEVELOPERS GOOD FOR RED COLORING WELLA AKTIENGESELLSCHAFT (DE) 1989-01-10 US claimed
US-4713080-A OXIDATIVE COLORING WELLA AKTIENGESELLSCHAFT (DE) 1987-12-15 US claimed
EP-0226072-A1 Oxidation dye containing 4-amino-2-aminomethyl phenol Wella Aktiengesellschaft (DE) 1987-06-24 EP claimed
WO-1987003475-A2 OXIDIZING HAIR DYER BASED ON 4-AMINO-2-AMINOMETHYLPHENOLS WELLA AKTIENGESELLSCHAFT (DE) 1987-06-18 WO claimed
US-4323360-A Dyeing compositions for hair which contain 2,4-diamino-butoxybenzene and/or a salt thereof as the coupling agent L'OREAL (FR) 1982-04-06 US claimed
US-4305717-A P-PHENYLENEDIAMINE OXIDIZING BASE AND COUPLER TO FORM INDAMINES L'OREAL (FR) 1981-12-15 US claimed
US-4149848-A N-/TETRAHYDROFURFURYL/P-PHENYLENEDIAMINES L'OREAL (FR) 1979-04-17 US claimed
US-4094635-A Meta-aminophenol sulfonamides as couplers in hair dye compositions L'OREAL (FR) 1978-06-13 US claimed