SCHEMBL109613

SCHEMBL109613

Nc1ccc(OC(O)CO)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.42
ALDH1A1 P00352 5/20 0.42
TSHR P16473 2/20 0.42
CYP3A4 P08684 2/20 0.42
MAPK1 P28482 1/20 0.39
APP P05067 2/20 0.39
MAOA P21397 3/20 0.37
MAPT P10636 5/20 0.35
MAOB P27338 2/20 0.35
TEAD4 Q15561 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
GAA P10253 2/20 0.35
PARP10 Q53GL7 1/20 0.35
RAB9A P51151 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 1/20 0.34
MITF O75030 1/20 0.34
GFER P55789 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9794570 0.98 TDP1 (0.41) TDP1ALDH1A1TSHRCYP3A4MAPK1
Water SCHEMBL9794578 0.98 TDP1 (0.41) TDP1ALDH1A1TSHRCYP3A4MAPK1
Hydrochloric Acid SCHEMBL9794561 0.96 TDP1 (0.40) TDP1ALDH1A1TSHRCYP3A4MAPK1
SCHEMBL183507 0.89 TSHR (0.33) TSHRMAPK1PARP10KMT2APOLB
SCHEMBL11706950 0.83 TDP1 (0.40) TDP1ALDH1A1TSHRCYP3A4MAPK1
SCHEMBL625947 0.83 TDP1 (0.42) TDP1ALDH1A1TSHRCYP3A4MAPK1
SCHEMBL9704893 0.81 TDP1 (0.41) TDP1ALDH1A1TSHRCYP3A4MAPK1
Hydrochloric Acid SCHEMBL27926179 0.81 TDP1 (0.41) TDP1ALDH1A1TSHRCYP3A4MAPK1
Hydrochloric Acid SCHEMBL9771748 0.81 TDP1 (0.41) TDP1ALDH1A1TSHRCYP3A4MAPK1
SCHEMBL8917076 0.80 ESR2 (0.44) ALDH1A1TSHRCYP3A4MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1880 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622856-B2 Agent for oxidative dyeing of keratin fibers, containing isatin and at least one defined polymer HENKEL AG & CO. KGAA (DE) 2026-05-12 US claimed
WO-2025061319-A2 IMPROVING THE WASHING FASTNESS OF LEVEL 2 COLORATIONS BY MEANS OF A SEALING PROCESS USING SILANES HENKEL AG & CO. KGAA (DE) 2025-03-27 WO claimed
EP-4496556-A1 AGENT FOR OXIDATIVELY DYEING KERATIN FIBERS, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE DEVELOPER TYPE, AT LEAST ONE OXIDATION DYE PRECURSOR OF THE COUPLER TYPE AND ISATIN Henkel AG & Co. KGaA (DE) 2025-01-29 EP claimed
EP-4496559-A1 AGENT FOR OXIDATIVE DYEING OF KERATIN FIBRES, CONTAINING ISATIN AND AT LEAST ONE DEFINED POLYMER Henkel AG & Co. KGaA (DE) 2025-01-29 EP claimed
EP-4496558-A1 MEANS FOR OXIDATIVELY DYEING KERATIN FIBRES, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE DEVELOPER TYPE, ISATIN AND AT LEAST ONE DETERMINED ALKALISING AGENT Henkel AG & Co. KGaA (DE) 2025-01-29 EP claimed
EP-4496555-A1 MEANS FOR OXIDATIVELY DYEING KERATIN FIBRES, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE P-PHENYLENEDIAMINE TYPE, ISATIN AND AT LEAST ONE OXIDISING AGENT Henkel AG & Co. KGaA (DE) 2025-01-29 EP claimed
US-20250025395-A1 Means for Oxidatively Dyeing Keratin Fibers HENKEL AG & CO. KGAA (DE) 2025-01-23 US claimed
US-20250025399-A1 AGENT FOR OXIDATIVELY DYEING KERATIN FIBERS, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE DEVELOPER TYPE AND ISATIN HENKEL AG & CO. KGAA (DE) 2025-01-23 US claimed
US-20250017837-A1 AGENT FOR OXIDATIVELY DYEING KERATIN FIBERS HENKEL AG & CO. KGAA (DE) 2025-01-16 US claimed
US-20250017838-A1 Agent for Oxidatively Dyeing Keratin Fibers HENKEL AG & CO. KGAA (DE) 2025-01-16 US claimed
US-5380340-A Hair dye containing aminopyrazole derivatives as well as pyrazole derivatives WELLA AKTIENGESELLSCHAFT (DE) 1995-01-10 US claimed
EP-0375977-B1 Oxidation hairdyeing composition based upon diaminopyrazole derivatives, and these diaminopyrazole derivatives WELLA AG (DE) 1994-02-02 EP claimed
EP-0395837-B1 OXIDATION HAIR DYES BASED ON 4-AMINOPHENOL DERIVATIVES AS WELL AS NEW 4-AMINOPHENOL DERIVATIVES Wella Aktiengesellschaft (DE) 1993-04-14 EP claimed
EP-0485544-A1 OXIDATIVE HAIR DYE CONTAINING 3-AMINOPHENOL DERIVATIVES, PROCESS FOR OXIDATIVE DYEING OF HAIR AND NEW 3-AMINOPHENOL DERIVATIVES. WELLA AG (DE) 1992-05-20 EP claimed
WO-1991018583-A1 OXIDATIVE HAIR DYE CONTAINING 3-AMINOPHENOL DERIVATIVES, PROCESS FOR OXIDATIVE DYEING OF HAIR AND NEW 3-AMINOPHENOL DERIVATIVES WELLA AKTIENGESELLSCHAFT (DE) 1991-12-12 WO claimed
EP-0226072-B1 OXIDATION DYE CONTAINING 4-AMINO-2-AMINOMETHYL PHENOL Wella Aktiengesellschaft (DE) 1991-04-10 EP claimed
US-4797130-A DYE DEVELOPERS GOOD FOR RED COLORING WELLA AKTIENGESELLSCHAFT (DE) 1989-01-10 US claimed
WO-1987003475-A2 OXIDIZING HAIR DYER BASED ON 4-AMINO-2-AMINOMETHYLPHENOLS WELLA AKTIENGESELLSCHAFT (DE) 1987-06-18 WO claimed
EP-0182187-A1 Oxidative dyestuff compositions for dyeing the hair, consisting of 4-amino-2-hydroxyalkyl phenols Wella Aktiengesellschaft (DE) 1986-05-28 EP claimed
WO-1986002829-A1 OXIDATION-TYPE HAIR-DYEING MEANS BASED ON 4-AMINO-2-HYDROXYALKYL-PHENOLS WELLA AKTIENGESELLSCHAFT (DE) 1986-05-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250017837-A1 AGENT FOR OXIDATIVELY DYEING KERATIN FIBERS KRT18, OAT, SQOR TDP1 2694/4885ALDH1A1 130/4885TSHR 4360/4885
US-20250025399-A1 AGENT FOR OXIDATIVELY DYEING KERATIN FIBERS, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE DEVELOPER TYPE AND ISATIN OAT, KRT18, ARG2 TDP1 2248/4885ALDH1A1 556/4885TSHR 4749/4885
US-12622856-B2 Agent for oxidative dyeing of keratin fibers, containing isatin and at least one defined polymer KRT18, ARSA, MKI67 TDP1 1412/4885ALDH1A1 433/4885TSHR 2813/4885
US-20250017838-A1 Agent for Oxidatively Dyeing Keratin Fibers KRT18, SQOR, ADH4 TDP1 2923/4885ALDH1A1 183/4885TSHR 3539/4885
US-20250025395-A1 Means for Oxidatively Dyeing Keratin Fibers KRT18, SQOR, ADH4 TDP1 3891/4885ALDH1A1 323/4885TSHR 4573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.