SCHEMBL9704893

SCHEMBL9704893

[CH2]CC(O)Oc1ccc(N)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.41
ALDH1A1 P00352 4/20 0.41
TSHR P16473 2/20 0.41
CYP3A4 P08684 2/20 0.41
MAPK1 P28482 1/20 0.38
MAOA P21397 3/20 0.35
MAPT P10636 5/20 0.34
MAOB P27338 3/20 0.34
TEAD4 Q15561 1/20 0.34
GAA P10253 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
PARP10 Q53GL7 1/20 0.34
RAB9A P51151 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
POLB P06746 1/20 0.33
MITF O75030 1/20 0.33
GFER P55789 1/20 0.33
NLRP1 Q9C000 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL625947 0.81 TDP1 (0.42) TDP1ALDH1A1TSHRCYP3A4MAPK1
SCHEMBL109613 0.81 TDP1 (0.42) TDP1ALDH1A1TSHRCYP3A4MAPK1
Hydrochloric Acid SCHEMBL9771748 0.79 TDP1 (0.41) TDP1ALDH1A1TSHRCYP3A4MAPK1
Water SCHEMBL9794578 0.79 TDP1 (0.41) TDP1ALDH1A1TSHRCYP3A4MAPK1
SCHEMBL8062984 0.79 CA12 (0.46) ALDH1A1TSHRCYP3A4MAPTSMN1; SMN2
Hydrochloric Acid SCHEMBL27926179 0.79 TDP1 (0.41) TDP1ALDH1A1TSHRCYP3A4MAPK1
Hydrochloric Acid SCHEMBL9794570 0.79 TDP1 (0.41) TDP1ALDH1A1TSHRCYP3A4MAPK1
SCHEMBL194634 0.78 LMNA (0.42) ALDH1A1TSHRL3MBTL1
SCHEMBL11706950 0.78 TDP1 (0.40) TDP1ALDH1A1TSHRCYP3A4MAPK1
Hydrochloric Acid SCHEMBL9794561 0.78 TDP1 (0.40) TDP1ALDH1A1TSHRCYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0205177-B1 METHOD OF ASSAYING MYOSIN LIGHT CHAIN Yamasa Shoyu Kabushiki Kaisha (JP) 1992-09-02 EP disclosed
EP-0478017-A1 Monoclonal antibody with specificity for human myosin light chains Yamasa Shoyu Kabushiki Kaisha (JP) 1992-04-01 EP disclosed
EP-0423333-A1 ANTI-ENDOSERINE ANTIBODY Yamasa Shoyu Kabushiki Kaisha (JP) 1991-04-24 EP disclosed
EP-0205177-A2 Method of assaying myosin light chain Yamasa Shoyu Kabushiki Kaisha (JP) 1986-12-17 EP disclosed
US-4342833-A CHEMICALLY BONDED TO CYA OGEN BROMIDE ACTIVATED AGAROSE BETHESDA RESEARCH LABORATORY (US) 1982-08-03 US disclosed
US-4180383-A Chamber holder for immobilized immunoadsorbent BECTON, DICKINSON AND COMPANY (US) 1979-12-25 US disclosed
US-4166102-A IMMOBILIZED IMMUNOADSORBENT BECTON, DICKINSON AND COMPANY (US) 1979-08-28 US disclosed
US-4108975-A REUSABLE IMMUNOADSORBENT BECTON, DICKINSON AND COMPANY (US) 1978-08-22 US disclosed
US-4108976-A AUTOMATED DIRECT SERUM RADIOIMMUNOASSAY BECTON, DICKINSON AND COMPANY (US) 1978-08-22 US disclosed
US-4059685-A Immobilized immunoadsorbent SUMMA CORPORATION (US) 1977-11-22 US disclosed
US-RE29480-E Method for determining vitamin B12 and reagent therefor PHARMACIA AB (SW) 1977-11-22 US disclosed
US-RE29474-E Method for the determination of proteins and polypeptides PHARMACIA AB (SW) 1977-11-15 US disclosed