Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.52 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10600114 | 0.85 | PRKCI (0.54) | NEU3DYRK1AALDH1A1HDAC1HDAC6 | |
| SCHEMBL7367784 | 0.84 | CA1 (0.58) | NEU3DYRK1AALDH1A1HDAC1HDAC6 | |
| SCHEMBL9995048 | 0.84 | CA1 (0.59) | F10NEU3DYRK1AALDH1A1HDAC1 | |
| SCHEMBL4398972 | 0.84 | HDAC1 (0.51) | F10NEU3DYRK1AALDH1A1HDAC1 | |
| SCHEMBL3891611 | 0.82 | NPC1 (0.64) | NEU3ALDH1A1HDAC1HDAC6NPC1 | |
| SCHEMBL141675 | 0.81 | NEU3 (0.60) | F10NEU3ALDH1A1HDAC1HDAC6 | |
| SCHEMBL4443570 | 0.81 | ALDH1A1 (0.51) | F10NEU3ALDH1A1HDAC1HDAC6 | |
| SCHEMBL3000834 | 0.80 | NEU3 (0.48) | F10NEU3DYRK1AALDH1A1HDAC1 | |
| SCHEMBL3050749 | 0.80 | RAB9A (0.49) | NEU3DYRK1AHDAC1HDAC6NPC1 | |
| SCHEMBL6170977 | 0.79 | PARP1 (0.53) | DYRK1AALDH1A1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581202-A2 | METHODS FOR THE TREATMENT OF PAIN AND TRAUMATIC INJURY USING BENZAMIDES AND COMPOSITIONS CONTAINING THE SAME | Renovis, Inc. (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004060286-A2 | METHODS FOR THE TREATMENT OF PAIN AND TRAUMATIC INJURY USING BENZAMIDES AND COMPOSITIONS CONTAINING THE SAME | RENOVIS, INC. (US) | 2004-07-22 | — | — | WO | disclosed |
| US-5215738-A | Used for destroying hypoxic tumor cells | SRI INTERNATIONAL (US) | 1993-06-01 | — | — | US | disclosed |
| US-5041653-A | Antitumor agents | SRI INTERNATIONAL (US) | 1991-08-20 | — | — | US | disclosed |
| US-5032617-A | Antitumor agents | SRI INTERNATIONAL (US) | 1991-07-16 | — | — | US | disclosed |
| EP-0190524-B1 | Industrial synthesis of N-[(1'-allyl-2'-pyrrolidinyl)methyl]-2-methoxy-4,5-azimido benzamide | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1991-03-06 | — | — | EP | disclosed |
| WO-1986006628-A1 | BENZAMIDE AND NICOTINAMIDE RADIOSENSITIZERS | SRI INTERNATIONAL (US) | 1986-11-20 | — | — | WO | disclosed |