SCHEMBL6259606

SCHEMBL6259606

CN(CCCO)S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 0.38
MMP1 P03956 9/20 0.38
MMP2 P08253 9/20 0.38
MMP9 P14780 9/20 0.38
MMP8 P22894 9/20 0.38
MMP13 P45452 9/20 0.38
CA1 P00915 8/20 0.38
F2 P00734 4/20 0.35
PRSS1 P07477 4/20 0.35
PRSS2 P07478 4/20 0.35
PRSS3 P35030 4/20 0.35
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL154402 0.95 MMP1 (0.37) CA2MMP1MMP2MMP9MMP8
SCHEMBL11057717 0.95 MMP1 (0.37) CA2MMP1MMP2MMP9MMP8
SCHEMBL7638386 0.94 CA2 (0.36) CA2MMP1MMP2MMP9MMP8
SCHEMBL7638909 0.93 CA2 (0.35) CA2MMP1MMP2MMP9MMP8
SCHEMBL23560633 0.92 CA2 (0.34) CA2MMP1MMP2MMP9MMP8
SCHEMBL8859625 0.90 CA2 (0.40) CA2MMP1MMP2MMP9MMP8
SCHEMBL8059110 0.90 CA2 (0.40) CA2MMP1MMP2MMP9MMP8
SCHEMBL10408556 0.90 CA2 (0.40) CA2MMP1MMP2MMP9MMP8
SCHEMBL6338088 0.90 CA2 (0.40) CA2MMP1MMP2MMP9MMP8
SCHEMBL10409852 0.90 CA2 (0.40) CA2MMP1MMP2MMP9MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005063842-A1 (POLY-)URETDIONES COMPRISING CHEMICALLY COUPLED PERFLUOROALKYL COMPOUNDS, AND METHOD FOR THE PRODUCTION THEREOF INSTITUT FÜR POLYMERFORSCHUNG DRESDEN E.V. (DE) 2005-07-14 WO disclosed