SCHEMBL8059110

SCHEMBL8059110

CN(CCO)S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 10/20 0.40
CA1 P00915 9/20 0.40
MMP1 P03956 9/20 0.40
MMP2 P08253 9/20 0.40
MMP9 P14780 9/20 0.40
MMP8 P22894 9/20 0.40
MMP13 P45452 9/20 0.40
F2 P00734 4/20 0.37
PRSS1 P07477 4/20 0.37
PRSS2 P07478 4/20 0.37
PRSS3 P35030 4/20 0.37
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6338088 1.00 CA2 (0.40) CA2CA1MMP1MMP2MMP9
SCHEMBL10409852 1.00 CA2 (0.40) CA2CA1MMP1MMP2MMP9
SCHEMBL10408556 1.00 CA2 (0.40) CA2CA1MMP1MMP2MMP9
SCHEMBL8859647 1.00 CA2 (0.40) CA2CA1MMP1MMP2MMP9
SCHEMBL8859625 1.00 CA2 (0.40) CA2CA1MMP1MMP2MMP9
SCHEMBL154446 0.98 CA2 (0.38) CA2CA1MMP1MMP2MMP9
SCHEMBL3189611 0.93 CA1 (0.33) CA2CA1MMP1MMP2MMP9
SCHEMBL6259606 0.90 CA2 (0.38) CA2CA1MMP1MMP2MMP9
SCHEMBL154402 0.88 MMP1 (0.37) CA2CA1MMP1MMP2MMP9
SCHEMBL11057717 0.88 MMP1 (0.37) CA2CA1MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0710262-B1 ORGANIC AEROGELS HUNTSMAN ICI CHEM LLC (US) 2000-06-14 EP disclosed
EP-0605105-B1 Process for rigid foams ICI PLC (GB) 1999-05-06 EP disclosed
US-5672673-A WATER-SOLUBLE WETTING AGENTS COMPRISING POLYETHERURETHANE MODIFIED BY AN N-PERFLUOROALKYLSULFAMIDOALKYL ALCOHOL AND A TERTIARY AMINO ALKYL ALCOHOL; ANTIAGGLOMERANTS; PIGMENTS BAYER AKTIENGESELLSCHAFT (DE) 1997-09-30 US disclosed
EP-0710262-A1 ORGANIC AEROGELS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1996-05-08 EP disclosed
US-5484818-A Organic aerogels IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1996-01-16 US disclosed
US-5393799-A Reacting reaction product of excess polyisocyanate and fluorinated isocyanate-reactive compound with polyfunctional reactive composition under foam-forming conditions IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-02-28 US disclosed
WO-1995003358-A1 ORGANIC AEROGELS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-02-02 WO disclosed
EP-0605105-A1 Process for rigid foams IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-07-06 EP disclosed
US-5254660-A Polyurethanes, fluoropolymers BAYER AKTIENGESELLSCHAFT (DE) 1993-10-19 US disclosed
US-4965159-A CORE, LAYER FOR CONTROLLING TRIBOELECTRIC CHARGING, AND FLUORINATED ALKYL METHACRYLATE KONICA CORPORATION (JP) 1990-10-23 US disclosed