Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.56 |
| ▸ | MAOB | P27338 | 6/20 | 0.56 |
| ▸ | ACHE | P22303 | 3/20 | 0.55 |
| ▸ | BCHE | P06276 | 2/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | SLC13A5 | Q86YT5 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626003 | 0.77 | MAOB (0.78) | MAOAMAOBACHEBCHEBACE1 | |
| SCHEMBL620669 | 0.73 | MAOA (1.00) | MAOAMAOBACHEBCHEBACE1 | |
| Hydrochloric Acid SCHEMBL620552 | 0.72 | MAOA (0.98) | MAOAMAOBACHEBCHEBACE1 | |
| Hydrochloric Acid SCHEMBL621934 | 0.72 | MAOA (0.98) | MAOAMAOBACHEBCHEBACE1 | |
| SCHEMBL608520 | 0.72 | ACHE (1.00) | MAOAMAOBACHEBCHEBACE1 | |
| SCHEMBL152388 | 0.71 | LMNA (0.56) | SLC13A5KDM4ELMNAGAA | |
| SCHEMBL608751 | 0.70 | ACHE (0.81) | MAOAMAOBACHEBCHEBACE1 | |
| SCHEMBL609069 | 0.69 | ACHE (0.83) | MAOAMAOBACHEBCHEBACE1 | |
| SCHEMBL610508 | 0.69 | ACHE (0.83) | MAOAMAOBACHEBCHEBACE1 | |
| SCHEMBL608665 | 0.69 | ACHE (0.75) | MAOAMAOBACHEBCHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603492-A1 | NEUROPROTECTIVE AND NEURO-RESTORATIVE IRON CHELATORS AND MONOAMINE OXIDASE INHIBITORS AND USES THEREOF | Varinel Inc. (US) | 2013-06-19 | — | — | EP | disclosed |
| WO-2012020389-A1 | NEUROPROTECTIVE AND NEURO-RESTORATIVE IRON CHELATORS AND MONOAMINE OXIDASE INHIBITORS AND USES THEREOF | VARINEL INC (US) | 2012-02-16 | — | — | WO | disclosed |