Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 2/20 | 0.55 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249634 | 1.00 | SRD5A1 (0.55) | SRD5A1HSD17B1LMNAMAPTRECQL | |
| SCHEMBL15308499 | 0.79 | SIGMAR1 (0.57) | SRD5A1ALDH1A1CYP3A4THRBMAPK1 | |
| SCHEMBL5559578 | 0.79 | SIGMAR1 (0.57) | SRD5A1ALDH1A1CYP3A4THRBMAPK1 | |
| SCHEMBL5559815 | 0.79 | SIGMAR1 (0.57) | SRD5A1ALDH1A1CYP3A4THRBMAPK1 | |
| SCHEMBL6247625 | 0.78 | ESR2 (0.48) | HSD17B1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL13923485 | 0.74 | SRD5A1 (0.49) | SRD5A1HSD17B1LMNAMAPTRECQL | |
| Hydrochloric Acid SCHEMBL10835629 | 0.74 | HTR2C (0.52) | SRD5A1HSD17B1LMNAMAPTRECQL | |
| SCHEMBL6569001 | 0.74 | LMNA (0.60) | SRD5A1HSD17B1LMNAMAPTRECQL | |
| SCHEMBL25529639 | 0.74 | LMNA (0.60) | SRD5A1HSD17B1LMNAMAPTRECQL | |
| SCHEMBL6565814 | 0.74 | SRD5A1 (0.52) | SRD5A1HSD17B1LMNAMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399406-B1 | NOVEL ESTROGEN RECEPTOR LIGANDS AND METHODS I | KAROBIO AB (SE) | 2005-08-10 | — | — | EP | disclosed |