Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.68 |
| ▸ | PGK1 | P00558 | 3/20 | 0.67 |
| ▸ | PGK2 | P07205 | 3/20 | 0.67 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.65 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428108 | 0.82 | PTPN1 (1.00) | PTPN1PGK1PGK2PTPN5PTPN2 | |
| Diphenylamine SCHEMBL27245439 | 0.77 | HSD17B10 (0.67) | — | |
| Diphenylamine SCHEMBL27245440 | 0.77 | HSD17B10 (0.67) | — | |
| Diphenylamine SCHEMBL28255754 | 0.77 | HSD17B10 (0.67) | — | |
| SCHEMBL503225 | 0.76 | ALDH1A1 (0.62) | — | |
| Hydrochloric Acid SCHEMBL2846563 | 0.74 | ALDH1A1 (0.59) | — | |
| Fluoride SCHEMBL8754786 | 0.74 | ALDH1A1 (0.59) | — | |
| SCHEMBL17115744 | 0.73 | NPC1 (0.81) | — | |
| SCHEMBL6838700 | 0.72 | PGK1 (0.78) | PTPN1PGK1PGK2PTPN5PTPN2 | |
| SCHEMBL2637465 | 0.72 | PGK1 (0.78) | PTPN1PGK1PGK2PTPN5PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1523323-A2 | REAGENTS AND METHODS FOR SMOOTH MUSCLE THERAPIES | Arizona Board of Regents (US) | 2005-04-20 | — | — | EP | disclosed |
| WO-2003018758-A2 | REAGENTS AND METHODS FOR SMOOTH MUSCLE THERAPIES | ARIZONA BOARD OF REGENTS (US) | 2003-03-06 | — | — | WO | disclosed |