SCHEMBL6260904

SCHEMBL6260904

Nc1ccc(N)c(S(=O)(=O)O)c1.Nc1ccc(S(=O)(=O)O)c(N)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.49
ALDH1A1 P00352 6/20 0.48
RECQL P46063 4/20 0.48
HSD17B10 Q99714 4/20 0.48
TSHR P16473 3/20 0.48
CASP1 P29466 2/20 0.48
THRB P10828 2/20 0.48
CYP3A4 P08684 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
TDP1 Q9NUW8 5/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
CASP6 P55212 3/20 0.46
POLB P06746 3/20 0.46
MAPT P10636 3/20 0.46
KDM4E B2RXH2 2/20 0.46
GAA P10253 2/20 0.46
NSD2 O96028 2/20 0.46
APEX1 P27695 2/20 0.46
APOBEC3A P31941 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL343300 0.92 ALDH1A1 (0.50) RAPGEF4ALDH1A1RECQLHSD17B10TSHR
SCHEMBL115254 0.92 ALDH1A1 (0.55) RAPGEF4ALDH1A1RECQLHSD17B10TSHR
SCHEMBL29349546 0.92 ALDH1A1 (0.55) RAPGEF4ALDH1A1RECQLHSD17B10TSHR
SCHEMBL11426855 0.90 RAPGEF4 (0.49) RAPGEF4ALDH1A1RECQLHSD17B10TSHR
SCHEMBL3396551 0.90 RAPGEF4 (0.49) RAPGEF4ALDH1A1RECQLHSD17B10TSHR
SCHEMBL6028415 0.90 RAPGEF4 (0.49) RAPGEF4ALDH1A1RECQLHSD17B10TSHR
Ammonia Solution, Strong SCHEMBL7554182 0.90 RAPGEF4 (0.49) RAPGEF4ALDH1A1RECQLHSD17B10TSHR
SCHEMBL10487045 0.90 ALDH1A1 (0.53) RAPGEF4ALDH1A1RECQLHSD17B10TSHR
Hydrochloric Acid SCHEMBL8641895 0.90 RAPGEF4 (0.49) RAPGEF4ALDH1A1RECQLHSD17B10TSHR
Ammonia Solution, Strong SCHEMBL7554180 0.90 RAPGEF4 (0.49) RAPGEF4ALDH1A1RECQLHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005073265-A1 CONJUGATED THIOPHENES HAVING CONDUCTING PROPERTIES AND SYNTHESIS OF SAME UNIVERSITE DE MONTREAL (CA) 2005-08-11 WO disclosed
US-6805718-B2 USING AROMATIC AMINE, NAPHTHOL OR AMINONAPHTHALENE AND ENZYME NOVOZYMES A/S (DK) 2004-10-19 US disclosed
US-20030226215-A1 Enzymatic method for textile dying NOVOZYMES NORTH AMERICA, INC. (US) 2003-12-11 US disclosed
US-20010037532-A1 Enzymatic method for textile dyeing NOVOZYMES A/S (DK) 2001-11-08 US disclosed
US-6296672-B1 PEROXIDASE, OXIDOREDUCTASE, LACCASE NOVOZYMES A/S PATENTS (DK) 2001-10-02 US disclosed
EP-0503339-B1 Reactive azo dyes with a hydroxypyridon coupling component BASF AG (DE) 1994-06-22 EP disclosed
EP-0503339-A1 Reactive azo dyes with a hydroxypyridon coupling component BASF Aktiengesellschaft (DE) 1992-09-16 EP disclosed
US-4678611-A Novel dyestuff intermediates and use thereof for the manufacture of novel azo dyes CIBA-GEIGY CORPORATION (US) 1987-07-07 US disclosed
US-4360460-A Novel azo dyes having a 4-sulfo-5-aminomethyl naphthalene coupling moiety CIBA-GEIGY AG (CH) 1982-11-23 US disclosed
US-4288363-A Novel azo dyes having 2-amino-5-aminomethyl-7-sulfo naphthalene coupling moiety CIBA-GEIGY CORPORATION (US) 1981-09-08 US disclosed
EP-0024668-A2 Reactive dyestuffs and their use in dyeing and printing hydroxyl groups and nitrogen containing materials BAYER AG (DE) 1981-03-11 EP disclosed