Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.33 |
| ▸ | NR1D1 | P20393 | 3/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | MMP8 | P22894 | 2/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6264266 | 0.91 | PTPN1 (0.37) | PTPN1ALDH1A1GAA | |
| SCHEMBL6263978 | 0.91 | PTPN1 (0.37) | PTPN1ALDH1A1NPSR1 | |
| SCHEMBL6265724 | 0.90 | NR1D1 (0.35) | PTPN1NR1D1MAPTALDH1A1MEN1 | |
| SCHEMBL6269183 | 0.85 | PTPN1 (0.45) | PTPN1 | |
| SCHEMBL3910215 | 0.84 | PTPN1 (0.45) | PTPN1 | |
| SCHEMBL6265087 | 0.84 | PTPN1 (0.43) | PTPN1 | |
| SCHEMBL6265898 | 0.82 | PTPN1 (0.40) | PTPN1 | |
| SCHEMBL6264094 | 0.82 | PTPN1 (0.41) | PTPN1SLC6A3 | |
| SCHEMBL6263443 | 0.81 | PTPN1 (0.40) | PTPN1SLC6A3 | |
| SCHEMBL6267674 | 0.81 | PTPN1 (0.36) | PTPN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |