Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 4/20 | 0.34 |
| ▸ | TACR1 | P25103 | 3/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6263978 | 0.92 | PTPN1 (0.37) | PTPN1RORCALDH1A1 | |
| SCHEMBL6261192 | 0.91 | PTPN1 (0.33) | PTPN1GAAALDH1A1 | |
| SCHEMBL6265724 | 0.86 | NR1D1 (0.35) | PTPN1ALDH1A1 | |
| SCHEMBL3910215 | 0.85 | PTPN1 (0.45) | PTPN1 | |
| SCHEMBL6267171 | 0.85 | PTPN1 (0.52) | PTPN1PPARGPPARDPPARA | |
| SCHEMBL6265087 | 0.85 | PTPN1 (0.43) | PTPN1TACR1 | |
| SCHEMBL6263443 | 0.85 | PTPN1 (0.40) | PTPN1 | |
| SCHEMBL6262829 | 0.83 | PTPN1 (0.41) | PTPN1 | |
| SCHEMBL6264094 | 0.83 | PTPN1 (0.41) | PTPN1 | |
| SCHEMBL6262467 | 0.82 | PTPN1 (0.45) | PTPN1PPARGPPARDPPARATACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |