Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 6/20 | 0.42 |
| ▸ | MAP3K12 | Q12852 | 11/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626269 | 0.84 | F2RL3 (0.44) | PIK3CAMAP3K12F2RL3CYP3A4 | |
| SCHEMBL626288 | 0.84 | PIK3CA (0.51) | PIK3CAKCNH2FYN | |
| SCHEMBL626702 | 0.83 | MAP3K12 (0.43) | PIK3CAMAP3K12F2RL3 | |
| SCHEMBL626145 | 0.82 | F2RL3 (0.43) | PIK3CAMAP3K12F2RL3CYP3A4 | |
| SCHEMBL625236 | 0.80 | MAP3K12 (0.45) | PIK3CAMAP3K12 | |
| SCHEMBL624389 | 0.80 | MAP3K12 (0.43) | PIK3CAMAP3K12F2RL3 | |
| SCHEMBL625673 | 0.79 | MAP3K12 (0.48) | PIK3CAMAP3K12F2RL3 | |
| SCHEMBL12474086 | 0.79 | PIK3CA (0.47) | PIK3CAMAP3K12F2RL3CYP3A4 | |
| SCHEMBL624442 | 0.79 | PIK3CA (0.44) | PIK3CAMAP3K12F2RL3CYP3A4 | |
| SCHEMBL626299 | 0.77 | PIK3CA (0.47) | PIK3CAMAP3K12F2RL3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |