Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.44 |
| ▸ | MAP3K12 | Q12852 | 10/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626145 | 0.94 | F2RL3 (0.43) | F2RL3PIK3CAMAP3K12CYP3A4PIK3CD | |
| SCHEMBL12474086 | 0.86 | PIK3CA (0.47) | F2RL3PIK3CAMAP3K12CYP3A4PIK3CD | |
| SCHEMBL624442 | 0.86 | PIK3CA (0.44) | F2RL3PIK3CAMAP3K12CYP3A4PIK3CD | |
| SCHEMBL626289 | 0.84 | PIK3CA (0.42) | F2RL3PIK3CAMAP3K12CYP3A4 | |
| SCHEMBL626299 | 0.84 | PIK3CA (0.47) | F2RL3PIK3CAMAP3K12CYP3A4PIK3CD | |
| SCHEMBL626625 | 0.84 | PIK3CA (0.43) | F2RL3PIK3CAMAP3K12CYP3A4PIK3CD | |
| SCHEMBL625400 | 0.83 | PIK3CA (0.43) | F2RL3PIK3CAMAP3K12CYP3A4PIK3CD | |
| SCHEMBL626774 | 0.81 | PIK3CA (0.42) | F2RL3PIK3CAMAP3K12CYP3A4PIK3CD | |
| SCHEMBL627611 | 0.81 | MAP3K12 (0.43) | F2RL3PIK3CAMAP3K12PIK3CDPIK3CB | |
| SCHEMBL626702 | 0.81 | MAP3K12 (0.43) | F2RL3PIK3CAMAP3K12PIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |